Abstract

The MBRS Program of the UPR Medical Sciences Campus has two principal goals; to help faculty establish a productive research program and to stimulate hispanic students to choose a career in biomedical research. The two goals are mutually interdependent; the best way to stimulate students is to have them work in a productive research environment; and having enthusiastic students in a laboratory is an effective mechanism to perform studies and to facilitate ongoing research programs. With the support of MBRS, investigators can accumulate enough data to apply for independent research support. This program provides graduate and undergraduate students of the UPR Medical Sciences Campus and Rio Piedras Campus opportunities for research in the biomedical sciences. In addition, the Program envisions to facilitate the participation of young investigators in order to compete on a more equal basis with researchers from more gifted institutions. In this proposal we have 17 research subprojects of which three are associate investigators. These projects cover the areas of pharmacology, molecular biology, renal physiology, obstetrics, microbiology, chemical carcinogenesis and neurobiology.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
5S06GM008224-10
Application #
2167610
Study Section
Special Emphasis Panel (SRC (01))
Project Start
1985-05-01
Project End
1996-07-31
Budget Start
1994-08-01
Budget End
1995-07-31
Support Year
10
Fiscal Year
1994
Total Cost
Indirect Cost

  Institution

Name
University of Puerto Rico Med Sciences
Department
Type
Schools of Medicine
DUNS #
City
San Juan
State
PR
Country
United States
Zip Code
00936

  Publications

Rijpma, Sanna R; van der Velden, Maarten; González-Pons, Maria et al. (2016) Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites. Cell Microbiol 18:369-83
Padín-Irizarry, Vivian; Colón-Lorenzo, Emilee E; Vega-Rodríguez, Joel et al. (2016) Glutathione-deficient Plasmodium berghei parasites exhibit growth delay and nuclear DNA damage. Free Radic Biol Med 95:43-54
Jardón, Javier; Izquierdo, Natalio J; Renta, Jessica Y et al. (2016) Ocular Findings in Patients with the Hermansky-Pudlak Syndrome (Types 1 and 3). Ophthalmic Genet 37:89-94
Rivera-Peña, Bianca; Ruíz-Fullana, Francisco J; Vélez-Reyes, Germán L et al. (2016) HPV-16 infection modifies overall survival of Puerto Rican HNSCC patients. Infect Agent Cancer 11:47
Velásquez-Martínez, Maria C; Vázquez-Torres, Rafael; Rojas, Legier V et al. (2015) Alpha-1 adrenoreceptors modulate GABA release onto ventral tegmental area dopamine neurons. Neuropharmacology 88:110-21
Vega-Rodríguez, Joel; Pastrana-Mena, Rebecca; Crespo-Lladó, Keila N et al. (2015) Implications of Glutathione Levels in the Plasmodium berghei Response to Chloroquine and Artemisinin. PLoS One 10:e0128212
Zenón, Frances; Cantres-Rosario, Yisel; Adiga, Radhika et al. (2015) HIV-infected microglia mediate cathepsin B-induced neurotoxicity. J Neurovirol 21:544-58
Ortiz, A P; Unger, E R; Muñoz, C et al. (2014) Cross-sectional study of HPV-16 infection in a population-based subsample of Hispanic adults. BMJ Open 4:e004203
Rosas, Odrick R; Torrado, Aranza I; Santiago, Jose M et al. (2014) Long-term treatment with PP2 after spinal cord injury resulted in functional locomotor recovery and increased spared tissue. Neural Regen Res 9:2164-73
Mosquera, Laurivette; Colón, Jennifer M; Santiago, José M et al. (2014) Tamoxifen and estradiol improved locomotor function and increased spared tissue in rats after spinal cord injury: their antioxidant effect and role of estrogen receptor alpha. Brain Res 1561:11-22

Showing the most recent 10 out of 174 publications