The Minorities in Research and Science Achievement Program at the University of Texas at San Antonio is intended to (1) improve the biomedical research capabilities of the faculty and university, (2) provide research opportunities for students at the undergraduate and graduate levels, and (3) expose minority science students to a variety of scientists and their research. To achieve these ends, eleven principal investigators, two co-principal investigators, and six associate research faculty will provide research opportunities and guidance in specific biomedical research projects. The seventeen research projects will include (1) the sensitivity of mosquitoes and filarial nematodes to chemical mutagens, (2) intestinal interactions in pathogenic vibrio, (3) the correlation of enantiomeric selection inthe asymmetric synthesis of amino acids, (4) the effects of environmental pollutants on microbial metabolism, (5) biochemistry of the purple membrane proton pump, (6) biochemistry of metallic model systems, (7) synthesis and biochemical properties of the glyco-protein inhibitor, swainsonine, (8) the laboratory synthesis of hypertensive drugs, (9) biochemical and physiological pathways of vertebrate vision, (10) the neuro-physiology of the hypothalamus, (11) the application of colchicine derivatives in tubulin, (12) the virulence of pathogenic trichomonas, (13) molecular pathogenesis of mycoplasma, (14) the cloning of bacterial promoters, (15) experimental autoimmune Myasthermia Gravis (16) the pharmacological effects of organophosphorus anticholinesterase compounds, and (17) the regulation of immunoglobulin expression. The students' research potential will be enhanced by exposing them to sophisticated equipment and modern research techniques employed in the biochemical, chemical, genetic, microbiological, pharmacological and physiological disciplines. Likewise, all students will interact with several regional and national scientists activelyn involved in biomedical research. An institutional seminar-class program will be conducted with outstanding professionals from other institutions. Attendance at regional and/or national scientific meetings will also be strongly encouraged.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
5S06RR008194-07
Application #
3514173
Study Section
General Research Support Program Advisory Committee (GRS)
Project Start
1983-09-01
Project End
1987-08-31
Budget Start
1986-09-01
Budget End
1987-08-31
Support Year
7
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Type
Schools of Arts and Sciences
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78249
Vaughan, M K; Vaughan, G M; Chenoweth, P C et al. (1991) Harderian gland porphyrin, lysosomal and type II 5'-deiodinase rhythms in Sprague-Dawley and Fischer-344 rats kept under chronic long- or short-photoperiod conditions. Int J Biochem 23:919-24
Denny, J B; Polan-Curtain, J; Wayner, M J et al. (1991) Angiotensin II blocks hippocampal long-term potentiation. Brain Res 567:321-4
Sanders-Sanchez, S R; Malsbury, D; Tsin, A T (1990) Comparison of retinal pigment epithelium cell preparations from the bovine eye. Experientia 46:498-500
Felthauser, A M; Claiborne, B J (1990) Intracellular labeling of dentate granule cells in fixed tissue permits quantitative analysis of dendritic morphology. Neurosci Lett 118:249-51
Rihn, L L; Claiborne, B J (1990) Dendritic growth and regression in rat dentate granule cells during late postnatal development. Brain Res Dev Brain Res 54:115-24
Chambers, J P; Kumar, P; Tsin, A T et al. (1990) Partial characterization of a high affinity [Ca2+ + Mg2+]-dependent adenosinetriphosphatase from bovine retina. Exp Eye Res 50:127-34
Denny, J B; Polan-Curtain, J; Rodriguez, S et al. (1990) Evidence that protein kinase M does not maintain long-term potentiation. Brain Res 534:201-8
Phillips, T S; Tsin, A T; Reiter, R J et al. (1989) Retinoids in the bovine pineal gland. Brain Res Bull 22:259-61
Nasr-Schirf, D; Rodriguez, P H; Schirf, V R et al. (1989) Variation in four acid hydrolase activities in filarial-susceptible and -refractory genotypes of Aedes aegypti. Biochem Genet 27:533-9
Rodriguez, K A; Tsin, A T (1989) Retinyl esters in the vertebrate neuroretina. Am J Physiol 256:R255-8

Showing the most recent 10 out of 52 publications