This is a request for continued support for research training at the University of Iowa Center on Aging. The goals of the Interdisciplinary Research Training Program in Aging are: 1) to provide multidisciplinary research and training in mechanisms and consequences of aging, 2) to prepare fellows for academic careers in geriatrics and gerontology, and 3) to bring special emphasis on aging research to a broad spectrum of professional disciplines. The program focuses on research and training dedicated to understanding mechanisms of the aging process and addressing the needs of the elderly, particularly in a rural setting. The research training program is structured in 4 cores: cardiovascular and pulmonary disease in aging, mechanisms and consequences of aging, degenerative neurological disease and stroke, and social and psychological aspects of aging. The program builds on the strengths of existing research programs in aging and diseases of the patient. These include the Cardiovascular Research Center, Alzheimer's Disease Research Center, Center for Oral Health and Aging, and Gerontological Nursing Intervention Research Center. Several ongoing aging-related seminars, journal clubs, discussion groups, and meetings with the directors, are offered to trainees to provide multidisciplinary and broad-based educational opportunities. Research training is provided by 76 faculty sponsors from 8 colleges within the University: Medicine, Nursing, Dentistry, Liberal Arts, Business, Engineering, Pharmacy, and Education. The sponsors are experienced investigators with a commitment to aging research. Trainees work closely with their sponsors in a supportive research environment. Predoctoral trainees have a strong interest in aging and are medical or dental students, or candidates for a Ph.D. in pharmacology, physiology, nursing, preventive medicine and other appropriate disciplines. Postdoctoral research prepares fellows for academic careers in geriatrics or gerontology, or leads to careers in other specialties with an emphasis on studies of aging. Strengths of the program are 1) many productive, well-funded mentors, 2) national leaders in areas of research critical to the phenomenon and problems of aging, 3) strong institutional commitment to develop outstanding training and research programs in aging, 4) strong educational programs in aging, 5) a fine institutional record of training in relevant disci lines and 6 outstanding clinical and research facilities.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Institutional National Research Service Award (T32)
Project #
5T32AG000214-10
Application #
6168586
Study Section
Biological and Clinical Aging Review Committee (BCA)
Program Officer
Slater, Stanley L
Project Start
1991-07-01
Project End
2003-04-30
Budget Start
2000-05-01
Budget End
2003-04-30
Support Year
10
Fiscal Year
2000
Total Cost
$164,412
Indirect Cost
Name
University of Iowa
Department
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Erlen, Judith A; Stilley, Carol S; Bender, Ann et al. (2011) Personality traits and chronic illness: a comparison of individuals with psychiatric, coronary heart disease, and HIV/AIDS diagnoses. Appl Nurs Res 24:74-81
Anderson, Rozalyn M; Barger, Jamie L; Edwards, Michael G et al. (2008) Dynamic regulation of PGC-1alpha localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response. Aging Cell 7:101-11
Ichihara, Shigeru; Kitagawa, Norimichi; Akutsu, Hiromi (2007) Contrast and depth perception: effects of texture contrast and area contrast. Perception 36:686-95
Costanzo, Erin S; Lutgendorf, Susan K; Sood, Anil K et al. (2005) Psychosocial factors and interleukin-6 among women with advanced ovarian cancer. Cancer 104:305-13
Pashkova, Natasha; Catlett, Natalie L; Novak, Jennifer L et al. (2005) Myosin V attachment to cargo requires the tight association of two functional subdomains. J Cell Biol 168:359-64
Pashkova, Natasha; Catlett, Natalie L; Novak, Jennifer L et al. (2005) A point mutation in the cargo-binding domain of myosin V affects its interaction with multiple cargoes. Eukaryot Cell 4:787-98
Berke, Sarah J Shoesmith; Schmied, Francisca A Flores; Brunt, Ewout R et al. (2004) Caspase-mediated proteolysis of the polyglutamine disease protein ataxin-3. J Neurochem 89:908-18
Buchanan, Tony W; Karafin, Matthew S; Adolphs, Ralph (2003) Selective effects of triazolam on memory for emotional, relative to neutral, stimuli: differential effects on gist versus detail. Behav Neurosci 117:517-25
Stout, Julie C; Ready, Rebecca E; Grace, Janet et al. (2003) Factor analysis of the frontal systems behavior scale (FrSBe). Assessment 10:79-85
Duffy, Carol L; Phillips, Stacia L; Klingelhutz, Aloysius J (2003) Microarray analysis identifies differentiation-associated genes regulated by human papillomavirus type 16 E6. Virology 314:196-205

Showing the most recent 10 out of 36 publications