Infectious diseases are leading causes of morbidity and mortality worldwide. Increasingly, infectious agents are developing resistance to antimicrobials and antivirals; new strategies are needed to better control the spread of infection. The keys to these strategies lie in the interfaces among epidemiology, mathematics, statistics, microbiology and medicine. By applying population approaches to the study of infectious agents, new treatment and prevention strategies can be identified and evaluated. These complex problems require individuals trained to integrate information and skills across multiple disciplines. There is a severe shortage of individuals with this training. The goal of the Interdisciplinary training Program in Infectious Diseases (IPID) is to teach students to conduct multi-pronged studies in order to address problems arising from infectious agents that affect human health. This is a dual mentorship program: initially each student will be assigned two advisors each with expertise in a different core discipline. Students will be trained to conceptualize research problems using mathematical tools, to design appropriate population-based studies to address the problem using either laboratory or field methods, and to analyze and apply the study results. All students will gain practical expertise in the laboratory, in data collection, in data analysis, and in modeling. Following a year coursework, and opportunities to interact with faculty formally and informally, students will choose two mentors representing different core expertise to serve as mentors. This program is novel in that it formally integrates modeling techniques, and theoretical and practical experience in the laboratory and field. The ability to do so is extremely powerful. We are unaware of other programs in infectious disease which formally train students across these disciplines. IPlD is currently funded by the center for Molecular and Clinical Epidemiology of infectious Diseases (MAC-EPID) and the Center for the Study of Complex Systems (CSCS) and has four pre-doctoral students and one post-doctoral fellow. We are requesting funding for four pre-doctoral and two post-doctoral fellowships.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
1T32AI049816-01A1
Application #
6499905
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Mcsweegan, Edward
Project Start
2002-07-01
Project End
2007-06-30
Budget Start
2002-07-01
Budget End
2003-06-30
Support Year
1
Fiscal Year
2002
Total Cost
$123,112
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Bhavnani, Darlene; Bayas, Rosa de los Ángeles; Lopez, Velma K et al. (2016) Distribution of Enteroinvasive and Enterotoxigenic Escherichia coli Across Space and Time in Northwestern Ecuador. Am J Trop Med Hyg 94:276-84
Greene, Christine; Vadlamudi, Gayathri; Newton, Duane et al. (2016) The influence of biofilm formation and multidrug resistance on environmental survival of clinical and environmental isolates of Acinetobacter baumannii. Am J Infect Control 44:e65-71
Greene, Christine; Vadlamudi, Gayathri; Eisenberg, Marisa et al. (2015) Fomite-fingerpad transfer efficiency (pick-up and deposit) of Acinetobacter baumannii-with and without a latex glove. Am J Infect Control 43:928-34
Davis, Gregg S; Marino, Simeone; Marrs, Carl F et al. (2014) Phase variation and host immunity against high molecular weight (HMW) adhesins shape population dynamics of nontypeable Haemophilus influenzae within human hosts. J Theor Biol 355:208-18
Davis, Gregg S; Patel, May; Hammond, James et al. (2014) Prevalence, distribution, and sequence diversity of hmwA among commensal and otitis media non-typeable Haemophilus influenzae. Infect Genet Evol 28:223-32
Rosenthal, Mariana; Aiello, Allison E; Chenoweth, Carol et al. (2014) Impact of technical sources of variation on the hand microbiome dynamics of healthcare workers. PLoS One 9:e88999
Bhavnani, Darlene; Goldstick, Jason E; Cevallos, William et al. (2014) Impact of rainfall on diarrheal disease risk associated with unimproved water and sanitation. Am J Trop Med Hyg 90:705-11
Goldstick, Jason E; Trostle, James; Eisenberg, Joseph N S (2014) Ask when--not just whether--it's a risk: How regional context influences local causes of diarrheal disease. Am J Epidemiol 179:1247-54
Foxman, Betsy; Rosenthal, Mariana (2013) Implications of the human microbiome project for epidemiology. Am J Epidemiol 177:197-201
Marschall, Jonas; Piccirillo, Marilyn L; Foxman, Betsy et al. (2013) Patient characteristics but not virulence factors discriminate between asymptomatic and symptomatic E. coli bacteriuria in the hospital. BMC Infect Dis 13:213

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