Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
5T32CA073515-03
Application #
6172878
Study Section
Subcommittee G - Education (NCI)
Program Officer
Gorelic, Lester S
Project Start
1998-09-21
Project End
2003-07-31
Budget Start
2000-08-01
Budget End
2001-07-31
Support Year
3
Fiscal Year
2000
Total Cost
$109,677
Indirect Cost
Name
Case Western Reserve University
Department
Pathology
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Tobian, Aaron A R; Harding, Clifford V; Canaday, David H (2005) Mycobacterium tuberculosis heat shock fusion protein enhances class I MHC cross-processing and -presentation by B lymphocytes. J Immunol 174:5209-14
Tobian, Aaron A R; Canaday, David H; Boom, W Henry et al. (2004) Bacterial heat shock proteins promote CD91-dependent class I MHC cross-presentation of chaperoned peptide to CD8+ T cells by cytosolic mechanisms in dendritic cells versus vacuolar mechanisms in macrophages. J Immunol 172:5277-86
Pai, Rish K; Pennini, Meghan E; Tobian, Aaron A R et al. (2004) Prolonged toll-like receptor signaling by Mycobacterium tuberculosis and its 19-kilodalton lipoprotein inhibits gamma interferon-induced regulation of selected genes in macrophages. Infect Immun 72:6603-14
Sturm, Andreas; Krivacic, Kimberley A; Fiocchi, Claudio et al. (2004) Dual function of the extracellular matrix: stimulatory for cell cycle progression of naive T cells and antiapoptotic for tissue-derived memory T cells. J Immunol 173:3889-900
Tobian, Aaron A R; Canaday, David H; Harding, Clifford V (2004) Bacterial heat shock proteins enhance class II MHC antigen processing and presentation of chaperoned peptides to CD4+ T cells. J Immunol 173:5130-7
Goss, Valerie L; Cross, Janet V; Ma, Kaiwen et al. (2003) SAPK/JNK regulates cdc2/cyclin B kinase through phosphorylation and inhibition of cdc25c. Cell Signal 15:709-18
Wang, Zhengqi; Malone, Michael H; Thomenius, Michael J et al. (2003) Dexamethasone-induced gene 2 (dig2) is a novel pro-survival stress gene induced rapidly by diverse apoptotic signals. J Biol Chem 278:27053-8
Krivacic, Kimberly A; Levine, Alan D (2003) Extracellular matrix conditions T cells for adhesion to tissue interstitium. J Immunol 170:5034-44
Thomenius, Michael J; Wang, Nancy S; Reineks, Edmunds Z et al. (2003) Bcl-2 on the endoplasmic reticulum regulates Bax activity by binding to BH3-only proteins. J Biol Chem 278:6243-50
Garhart, Christine A; Nedrud, John G; Heinzel, Frederick P et al. (2003) Vaccine-induced protection against Helicobacter pylori in mice lacking both antibodies and interleukin-4. Infect Immun 71:3628-33

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