? This new Training Program in the Neurobiology of Drug Abuse focuses on brain mechanisms of drug use/abuse/dependence. The Program is interdisciplinary and offers training in gene expression, gene profiling, drug receptors, signal transduction, neurotransmitters and neuroanatomy of reward/reinforcement, animal models, behavioral effects of drugs, medications development, and brain imaging in animals and humans. The goal is to produce scientists who have a depth of expertise in their respective approach and a breadth of expertise in the neurobiology of drug abuse. In addition to an emphasis on technical research skills, this program will develop written and oral communications skills, the ability to critically assess papers, data and applications, familiarity with grant/contract/application writing, ethical awareness and knowledge of the cutting edge research problems and questions in the field of drug abuse. """"""""Hands-on"""""""" research, courses, journal clubs and meetings comprise the training. The Training Faculty derives from five departments and has a record of outstanding achievements. The core of the Faculty consists of long-standing NIDA-funded investigators, as well as other strong investigators whose work intersects the Drug Abuse area and who have a strong interest in expanding their work more formally in drug abuse. The Faculty includes experienced Full and Associate Professors as well a,' more junior investigators who add substantial expertise and who are committed to developing a program in Drug Abuse research. The Program is designed to support four predoctoral fellows after they have completed their Doctoral Qualifying exams, usually at the end of their second year. In addition, it is designed to support six postdoctoral fellows. The duration of support for any given trainee will vary from one year (the minimum) to three years (rarely, and the maximum) so that many trainees will have the opportunity for support. A large percentage of our previous trainees have desirable positions and have been very productive. ? ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Institutional National Research Service Award (T32)
Project #
1T32DA015040-01A1
Application #
6593249
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Babecki, Beth
Project Start
2003-07-07
Project End
2008-06-30
Budget Start
2003-07-07
Budget End
2004-06-30
Support Year
1
Fiscal Year
2003
Total Cost
$222,221
Indirect Cost
Name
Emory University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Swanger, Sharon A; Vance, Katie M; Acker, Timothy M et al. (2018) A Novel Negative Allosteric Modulator Selective for GluN2C/2D-Containing NMDA Receptors Inhibits Synaptic Transmission in Hippocampal Interneurons. ACS Chem Neurosci 9:306-319
Rojas, Asheebo; Wang, Wenyi; Glover, Avery et al. (2018) Beneficial Outcome of Urethane Treatment Following Status Epilepticus in a Rat Organophosphorus Toxicity Model. eNeuro 5:
DePoy, Lauren M; Zimmermann, Kelsey S; Marvar, Paul J et al. (2017) Induction and Blockade of Adolescent Cocaine-Induced Habits. Biol Psychiatry 81:595-605
Wheeler, Marina G; Duncan, Erica; Davis, Michael (2017) Low startle magnitude may be a behavioral marker of vulnerability to cocaine addiction. Synapse 71:46-50
Swanson, Andrew M; DePoy, Lauren M; Gourley, Shannon L (2017) Inhibiting Rho kinase promotes goal-directed decision making and blocks habitual responding for cocaine. Nat Commun 8:1861
Kuhar, Michael J; Job, Martin O (2017) CART Peptide Regulates Psychostimulant-Induced Activity and Exhibits a Rate Dependency. J Drug Alcohol Res 6:
Zimmermann, Kelsey S; Yamin, John A; Rainnie, Donald G et al. (2017) Connections of the Mouse Orbitofrontal Cortex and Regulation of Goal-Directed Action Selection by Brain-Derived Neurotrophic Factor. Biol Psychiatry 81:366-377
Job, Martin O; Kuhar, Michael J (2017) CART peptide in the nucleus accumbens regulates psychostimulants: Correlations between psychostimulant and CART peptide effects. Neuroscience 348:135-142
King, Lanikea B; Walum, Hasse; Inoue, Kiyoshi et al. (2016) Variation in the Oxytocin Receptor Gene Predicts Brain Region-Specific Expression and Social Attachment. Biol Psychiatry 80:160-169
Gaval-Cruz, Meriem; Goertz, Richard B; Puttick, Daniel J et al. (2016) Chronic loss of noradrenergic tone produces ?-arrestin2-mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens. Addict Biol 21:35-48

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