The objective of this program is to train post-doctoral scientists to pursue basic and applied scientific and engineering research on topics of importance to many sub-specialties in the field of radiology. During the past several decades, biomedical imaging-based specialties have increased greatly in number and magnitude; this trend is largely attributable to the accomplishments of the scientists and engineers who have developed and improved upon a variety of new, noninvasive or minimally invasive imaging technologies. The Department of Radiology at Brigham and Women's Hospital (BWH) and Harvard Medical School (HMS) is engaged in many research projects related to biomedical imaging and minimally- invasive therapies. Approximately half of the full-time faculty members of the department hold a Ph.D. degree, and almost 80% of BWH Radiology's NIH grant funding during the most recent fiscal year was procured and directed by Ph.D. or non-clinical M.D. principal investigators. The Radiology Department's clear commitment to fostering research in fundamental, image-based science and engineering within a multi- disciplinary clinical and research environment means that the proposed post-doctoral training program is demonstrably suited to train the next generation of biomedical imaging scientists. The proposed program will train up to 8 post-doctoral scientists at any given time, for a period of 2-3 years each. Before entering our program, trainees will have completed a doctoral degree, usually in a relevant field of science or engineering. Post-doctoral trainees will pursue research in one or more of the following sub-programs: experimental nuclear medicine, image-based informatics, image-guided tissue ablation, radiologic physics (MR, x-ray, CT), or surgical planning with 3D image reconstruction. Relevance: To sustain the significant advances in medical care that have resulted directly from research on new radiologic procedures, continuous replenishment of biomedical scientists from many disciplines ~ including physics, chemistry, biology, mathematics, engineering, and computer science - is needed. We believe that future biomedical imaging researchers are most likely to thrive in a combined clinical and research setting where they can learn from, and collaborate with, other scientists, as well as physicians. PERFORMANCE SITE ========================================Section End===========================================
| Kindlmann, Gordon; Tricoche, Xavier; Westin, Carl-Fredrik (2007) Delineating white matter structure in diffusion tensor MRI with anisotropy creases. Med Image Anal 11:492-502 |
| Kindlmann, Gordon; Ennis, Daniel B; Whitaker, Ross T et al. (2007) Diffusion tensor analysis with invariant gradients and rotation tangents. IEEE Trans Med Imaging 26:1483-99 |
| White, Phillip J; Clement, Greg T (2007) Two-dimensional localization with a single diffuse ultrasound field excitation. IEEE Trans Ultrason Ferroelectr Freq Control 54:2309-17 |
| White, P Jason; Palchaudhuri, Sonali; Hynynen, Kullervo et al. (2007) The effects of desiccation on skull bone sound speed in porcine models. IEEE Trans Ultrason Ferroelectr Freq Control 54:1708-10 |
| Kyriakos, Walid E; Hoge, W Scott; Mitsouras, Dimitris (2006) Generalized encoding through the use of selective excitation in accelerated parallel MRI. NMR Biomed 19:379-92 |
| Kindlmann, Gordon; Westin, Carl-Fredrik (2006) Diffusion tensor visualization with glyph packing. IEEE Trans Vis Comput Graph 12:1329-35 |
| Bergmann, Orjan; Kindlmann, Gordon; Lundervold, Arvid et al. (2006) Diffusion k-tensor estimation from Q-ball imaging using discretized principal axes. Med Image Comput Comput Assist Interv 9:268-75 |
| Kindlmann, Gordon; Tricoche, Xavier; Westin, Carl-Fredrik (2006) Anisotropy creases delineate white matter structure in diffusion tensor MRI. Med Image Comput Comput Assist Interv 9:126-33 |
| Ennis, Daniel B; Kindlmann, Gordon (2006) Orthogonal tensor invariants and the analysis of diffusion tensor magnetic resonance images. Magn Reson Med 55:136-46 |
| White, P J; Clement, G T; Hynynen, K (2006) Longitudinal and shear mode ultrasound propagation in human skull bone. Ultrasound Med Biol 32:1085-96 |
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