Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Institutional National Research Service Award (T32)
Project #
3T32EY007108-05S2
Application #
2161319
Study Section
Vision Research and Training Committee (VSN)
Project Start
1988-09-30
Project End
1995-05-31
Budget Start
1992-09-30
Budget End
1995-05-31
Support Year
5
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Washington University
Department
Genetics
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Wohlgemuth, J G; Bulboaca, G H; Moghadam, M et al. (1994) Physical mapping of origins of replication in the fission yeast Schizosaccharomyces pombe. Mol Biol Cell 5:839-49
Novack, D V; Korsmeyer, S J (1994) Bcl-2 protein expression during murine development. Am J Pathol 145:61-73
Petrash, J M; Tarle, I; Wilson, D K et al. (1994) Aldose reductase catalysis and crystallography. Insights from recent advances in enzyme structure and function. Diabetes 43:955-9
Carulli, J P; Chen, D M; Stark, W S et al. (1994) Phylogeny and physiology of Drosophila opsins. J Mol Evol 38:250-62
Wilson, D K; Tarle, I; Petrash, J M et al. (1993) Refined 1.8 A structure of human aldose reductase complexed with the potent inhibitor zopolrestat. Proc Natl Acad Sci U S A 90:9847-51
Carulli, J P; Krane, D E; Hartl, D L et al. (1993) Compositional heterogeneity and patterns of molecular evolution in the Drosophila genome. Genetics 134:837-45
Veis, D J; Sentman, C L; Bach, E A et al. (1993) Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes. J Immunol 151:2546-54
Veis, D J; Sorenson, C M; Shutter, J R et al. (1993) Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75:229-40
Petrash, J M; Harter, T; Tarle, I et al. (1993) Kinetic alteration of human aldose reductase by mutagenesis of cysteine residues. Adv Exp Med Biol 328:289-300
Tarle, I; Borhani, D W; Wilson, D K et al. (1993) Probing the active site of human aldose reductase. Site-directed mutagenesis of Asp-43, Tyr-48, Lys-77, and His-110. J Biol Chem 268:25687-93

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