Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007596-18
Application #
2166678
Study Section
Cellular and Molecular Basis of Disease Review Committee (CMBD)
Project Start
1978-07-01
Project End
1996-06-30
Budget Start
1995-07-01
Budget End
1996-06-30
Support Year
18
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Brandeis University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
616845814
City
Waltham
State
MA
Country
United States
Zip Code
02454
Turman, Daniel L; Cheloff, Abraham Z; Corrado, Alexis D et al. (2018) Molecular Interactions between a Fluoride Ion Channel and Synthetic Protein Blockers. Biochemistry 57:1212-1218
Wirth, Jacob D; Boucher, Jeffrey I; Jacobowitz, Joseph R et al. (2018) Functional and Structural Resilience of the Active Site Loop in the Evolution of Plasmodium Lactate Dehydrogenase. Biochemistry 57:6434-6442
Wong, Nathan R; Liu, Xinyue; Lloyd, Hannah et al. (2018) A new approach to understanding structure-function relationships in cytochromes P450 by targeting terpene metabolism in the wild. J Inorg Biochem 188:96-101
Last, Nicholas B; Stockbridge, Randy B; Wilson, Ashley E et al. (2018) A CLC-type F-/H+ antiporter in ion-swapped conformations. Nat Struct Mol Biol 25:601-606
Pádua, Ricardo A P; Sun, Yizhi; Marko, Ingrid et al. (2018) Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2. Nat Commun 9:4507
Winterstein, Laura-Marie; Kukovetz, Kerri; Rauh, Oliver et al. (2018) Reconstitution and functional characterization of ion channels from nanodiscs in lipid bilayers. J Gen Physiol 150:637-646
Pochapsky, Thomas C; Wong, Nathan; Zhuang, Yihao et al. (2018) NADH reduction of nitroaromatics as a probe for residual ferric form high-spin in a cytochrome P450. Biochim Biophys Acta Proteins Proteom 1866:126-133
Trieu, Melissa M; Devine, Erin L; Lamarche, Lindsey B et al. (2017) Expression, purification, and spectral tuning of RhoGC, a retinylidene/guanylyl cyclase fusion protein and optogenetics tool from the aquatic fungus Blastocladiella emersonii. J Biol Chem 292:10379-10389
Kumar, Ramasamy P; Morehouse, Benjamin R; Matos, Jason O et al. (2017) Structural Characterization of Early Michaelis Complexes in the Reaction Catalyzed by (+)-Limonene Synthase from Citrus sinensis Using Fluorinated Substrate Analogues. Biochemistry 56:1716-1725
Nguyen, Vy; Wilson, Christopher; Hoemberger, Marc et al. (2017) Evolutionary drivers of thermoadaptation in enzyme catalysis. Science 355:289-294

Showing the most recent 10 out of 86 publications