Abstract

The Program in Molecular Biology and Biotechnology proposes to create a training program in Cell and Molecular Biology. This program will train outstanding students in a broad interdisciplinary program covering all aspects of Cell and Molecular Biology. Participating faculty in the program will be drawn from the basic science departments of the School of Medicine, the Department of Biology from the School of Arts and Sciences and from the Department of Medicine. The students will receive their Ph.D. degrees in one of the participating departments or in the Curriculum in Genetics and Molecular Biology. A unified curriculum is described which will ensure that the students receive appropriate training. We are requesting support for recruitment of graduate students into this program. We are also requesting support for student travel and supplies for their research.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008581-05
Application #
6150920
Study Section
Special Emphasis Panel (ZGM1-CMB-6)
Program Officer
Zatz, Marion M
Project Start
1996-07-01
Project End
2002-06-30
Budget Start
2000-07-01
Budget End
2002-06-30
Support Year
5
Fiscal Year
2000
Total Cost
$154,473
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Biochemistry
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Perkowski, Ellen Foot; Miller, Brittany K; McCann, Jessica R et al. (2016) An orphaned Mce-associated membrane protein of Mycobacterium tuberculosis is a virulence factor that stabilizes Mce transporters. Mol Microbiol 100:90-107
Washington, Erica J; Mukhtar, M Shahid; Finkel, Omri M et al. (2016) Pseudomonas syringae type III effector HopAF1 suppresses plant immunity by targeting methionine recycling to block ethylene induction. Proc Natl Acad Sci U S A 113:E3577-86
Watson, Leah J; Rossi, Guendalina; Brennwald, Patrick (2014) Quantitative analysis of membrane trafficking in regulation of Cdc42 polarity. Traffic 15:1330-43
McCann, Jessica R; McDonough, Justin A; Sullivan, Jonathan Tabb et al. (2011) Genome-wide identification of Mycobacterium tuberculosis exported proteins with roles in intracellular growth. J Bacteriol 193:854-61
Alan, Jamie K; Berzat, Anastacia C; Dewar, Brian J et al. (2010) Regulation of the Rho family small GTPase Wrch-1/RhoU by C-terminal tyrosine phosphorylation requires Src. Mol Cell Biol 30:4324-38
Zimmerman, Eric I; Dollins, Claudia M; Crawford, Melissa et al. (2010) Lyn kinase-dependent regulation of miR181 and myeloid cell leukemia-1 expression: implications for drug resistance in myelogenous leukemia. Mol Pharmacol 78:811-7
Johnson, Søren M; Torrice, Chad D; Bell, Jessica F et al. (2010) Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition. J Clin Invest 120:2528-36
Summers, Daniel W; Douglas, Peter M; Ren, Hong-Yu et al. (2009) The type I Hsp40 Ydj1 utilizes a farnesyl moiety and zinc finger-like region to suppress prion toxicity. J Biol Chem 284:3628-39
Gates, Julie; Nowotarski, Stephanie H; Yin, Hongyan et al. (2009) Enabled and Capping protein play important roles in shaping cell behavior during Drosophila oogenesis. Dev Biol 333:90-107
Sullivan, Kelly D; Steiniger, Mindy; Marzluff, William F (2009) A core complex of CPSF73, CPSF100, and Symplekin may form two different cleavage factors for processing of poly(A) and histone mRNAs. Mol Cell 34:322-32

Showing the most recent 10 out of 26 publications