The Cellular and Molecular Pathology (CMP) Graduate Training Program is a joint venture of the UW-Madison Graduate School, the Department of Pathology and the School of Medicine and Public Health (SMPH). The Program draws 54 trainers from 20 departments across the UW graduate campus and Medical School, spanning 3 separate colleges (Medicine, Veterinary Medicine and Letters &Science). The goal of the CMP is to create a stimulating and robust intellectual interdisciplinary environment for predoctoral training embedded in an exciting and challenging basic and clinical translational research. CMP includes the active participation of basic research scientists and clinicians with a focus on understanding the pathogenesis of major human diseases and developing skills needed to move biological knowledge toward clinical application. The program has 28 PhD and 26 MD or MD/PhD funded faculty. We are requesting funds for training 2 predoctoral students in Year 1 and 4 in Years 2,3,4 and 5. Highly qualified candidates will be selected based on the recommendation of nominating CMP trainer, research experiences, letters of recommendation and potential to enhance diversity and make significant contributions toward the health-related research needs of our nation. Trainees will be supported by the training grant for no longer than 3 years. Our curriculum provides interdisciplinary and integrated training in fundamental concepts in modern pathobiology with an emphasis on biochemical, cellular and molecular approaches and rigorous in-depth research training in understanding of the fundamental bases of diseases. We engage our members in didactic pathobiology courses and translational clinical activities. We provide in-depth research training in the pathobiology of cancer, nervous system and immune system diseases. CMP also helps students to develop teaching and leadership skills. Increasing public demand for greater accountability for research expenditures and the need for converting basic science advances into clinical applications call for higher integration of medical training into graduate education. Our trainees will have fundamental knowledge and in-depth research experience in pathobiology combined with understanding of translational clinical research.

Public Health Relevance

The primary objective of the CMP Graduate Program is to prepare our graduates for productive careers in scientific research and education and to position them to make significant contributions toward the health-related research needs of our nation.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM081061-04
Application #
8500351
Study Section
Special Emphasis Panel (ZGM1-BRT-X (TR))
Program Officer
Cole, Alison E
Project Start
2010-07-01
Project End
2015-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
4
Fiscal Year
2013
Total Cost
$172,618
Indirect Cost
$8,490
Name
University of Wisconsin Madison
Department
Pathology
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Gimse, Kirstan; Gorzek, Ryan C; Olin, Andrew et al. (2018) Hippocampal Homer1b/c is necessary for contextual fear conditioning and group I metabotropic glutamate receptor mediated long-term depression. Neurobiol Learn Mem 156:17-23
Sutton, Matthew S; Ellis-Connell, Amy; Moriarty, Ryan V et al. (2018) Acute-Phase CD4+ T Cell Responses Targeting Invariant Viral Regions Are Associated with Control of Live Attenuated Simian Immunodeficiency Virus. J Virol 92:
Brown, Matthew E; Zhou, Ying; McIntosh, Brian E et al. (2018) A Humanized Mouse Model Generated Using Surplus Neonatal Tissue. Stem Cell Reports 10:1175-1183
McDaniel, Nellie K; Cummings, Christopher T; Iida, Mari et al. (2018) MERTK Mediates Intrinsic and Adaptive Resistance to AXL-targeting Agents. Mol Cancer Ther 17:2297-2308
Schmidt, Jenna Kropp; Block, Lindsey N; Golos, Thaddeus G (2018) Defining the rhesus macaque placental miRNAome: Conservation of expression of placental miRNA clusters between the macaque and human. Placenta 65:55-64
Contreras, Amanda; Beems, Megan V; Tatar, Andrew J et al. (2018) Co-transfer of tumor-specific effector and memory CD8+ T cells enhances the efficacy of adoptive melanoma immunotherapy in a mouse model. J Immunother Cancer 6:41
Mohr, Emma L; Block, Lindsey N; Newman, Christina M et al. (2018) Ocular and uteroplacental pathology in a macaque pregnancy with congenital Zika virus infection. PLoS One 13:e0190617
Hope, Chelsea; Emmerich, Philip B; Papadas, Athanasios et al. (2017) Versican-Derived Matrikines Regulate Batf3-Dendritic Cell Differentiation and Promote T Cell Infiltration in Colorectal Cancer. J Immunol 199:1933-1941
Nickells, Robert W; Schmitt, Heather M; Maes, Margaret E et al. (2017) AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury. Invest Ophthalmol Vis Sci 58:6091-6104
Sullivan, J A; Jankowska-Gan, E; Hegde, S et al. (2017) Th17 Responses to Collagen Type V, k?1-Tubulin, and Vimentin Are Present Early in Human Development and Persist Throughout Life. Am J Transplant 17:944-956

Showing the most recent 10 out of 84 publications