The goal of this proposal is to attain support for a new interdisciplinary program in Movement and Rehabilitation Sciences (MRS), created at Northwestern University under the umbrella of the Northwestern University Interdepartmental Neuroscience (NUIN) program. The mission of the NUIN-MRS program is to train students with clinical and life/applied science backgrounds to become rehabilitation scientists in basic, translational or clinical research. These rehabilitation scientists will have the ability to integrate knowledge from the various disciplines involved in MRS, including neuroscience and physiology, engineering and clinical sciences. The training program will focus on the neurobiology of movement and rehabilitation sciences, with three main goals: 1) understanding the neurobiology of movement behavior and disorders, 2) identifying and addressing the need for quantitative methods in MRS, and 3) applying this knowledge to the development of effective rehabilitation interventions. Northwestern University has a long and recognized history in the study of motor control, motor disability and recovery, and neural reorganization. Extensive research is performed in these areas at various levels, from basic animal and human studies focused on the control of movement and movement disorders to the development of novel rehabilitation interventions that address these movement disorders. The interdisciplinary nature of the program will allow close interaction between clinical investigators and basic and applied sciences investigators, providing a unique opportunity for training in translational research, going from the laboratory to the clinic. The PIs intend to support a total of 4 predoctoral students in year 1 of the training program and 7 trainees in each of years 2-5. The program will provide support for a total of two years for each trainee.

Public Health Relevance

The number of individuals with disabilities and the extent of the disabilities continue to increase with a clear impact on the need for developing better and more effective rehabilitation interventions. The proposed NUIN-MRS PhD program will train rehabilitation scientists based on solid fundamental science principles combined with quantitative methods to allow them to establish research programs to develop effective rehabilitation interventions and, more importantly, transfer them to the clinic.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Institutional National Research Service Award (T32)
Project #
5T32HD057845-02
Application #
8076874
Study Section
Pediatrics Subcommittee (CHHD)
Program Officer
Nitkin, Ralph M
Project Start
2010-07-01
Project End
2015-04-30
Budget Start
2011-07-01
Budget End
2012-04-30
Support Year
2
Fiscal Year
2011
Total Cost
$243,523
Indirect Cost
Name
Northwestern University at Chicago
Department
Physical Medicine & Rehab
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Belli, Hayley M; Yang, Anne E T; Bresee, Chris S et al. (2017) Variations in vibrissal geometry across the rat mystacial pad: base diameter, medulla, and taper. J Neurophysiol 117:1807-1820
Smith, Andrew C; Jakubowski, Kristen; Wasielewski, Marie et al. (2017) Lower extremity muscle structure in incomplete spinal cord injury: a comparison between ultrasonography and magnetic resonance imaging. Spinal Cord Ser Cases 3:17004
Kaloti, Aniket S; Johnson, Erik C; Bresee, Chris S et al. (2016) Representation of Stimulus Speed and Direction in Vibrissal-Sensitive Regions of the Trigeminal Nuclei: A Comparison of Single Unit and Population Responses. PLoS One 11:e0158399
Bush, Nicholas E; Schroeder, Christopher L; Hobbs, Jennifer A et al. (2016) Decoupling kinematics and mechanics reveals coding properties of trigeminal ganglion neurons in the rat vibrissal system. Elife 5:
Dragunas, Andrew C; Gordon, Keith E (2016) Body weight support impacts lateral stability during treadmill walking. J Biomech 49:2662-2668
Flint, Robert D; Scheid, Michael R; Wright, Zachary A et al. (2016) Long-Term Stability of Motor Cortical Activity: Implications for Brain Machine Interfaces and Optimal Feedback Control. J Neurosci 36:3623-32
Tan, Andrew Q; Shemmell, Jon; Dhaher, Yasin Y (2016) Downregulating Aberrant Motor Evoked Potential Synergies of the Lower Extremity Post Stroke During TMS of the Contralesional Hemisphere. Brain Stimul 9:396-405
Yu, Yan S W; Graff, Matthew M; Bresee, Chris S et al. (2016) Whiskers aid anemotaxis in rats. Sci Adv 2:e1600716
Weber 2nd, Kenneth A; Chen, Yufen; Wang, Xue et al. (2016) Lateralization of cervical spinal cord activity during an isometric upper extremity motor task with functional magnetic resonance imaging. Neuroimage 125:233-243
Weber 2nd, Kenneth A; Chen, Yufen; Wang, Xue et al. (2016) Functional magnetic resonance imaging of the cervical spinal cord during thermal stimulation across consecutive runs. Neuroimage 143:267-279

Showing the most recent 10 out of 27 publications