Because research into both animal and human reproductive biology has such widespread implications for human health we propose to establish a new Reproductive and Developmental Sciences Training Program (RDSTP) that will train young scientists to pursue research in High Priority Program Topic Areas identified by the NICHD/Fertility and Infertility (FI) Branch and the Gynecologic Health and Disease Branch. To provide training related to these NICHD target areas, the trainees in the proposed program will select from among four Areas of Specialization: Gonad and Gamete biology, Early Development, Reproductive Tract Biology and Gynecological Pathologies, and Environmental Factors impacting Reproduction, with multiple faculty trainers offering outstanding research opportunities and training environments in each of their specific areas of expertise. The Reproductive and Developmental Sciences program at Michigan State University has expanded extensively in the past six years with substantial institutional commitment, and is continuing to expand which provides a dynamic and rich environment for training young scientists. The RDSTP will pursue dual objectives of providing competence in emerging, cutting-edge, NICHD-recognized areas of high research interest, and providing essential skills for long-term career and professional development, with qualifications to participate in the broader roles of scientists in our community. The latter will include developing verbal and written communication skills, management and mentoring skills, career advancement skills, teaching skills, and other expertise that will be essential for future success in both academics as well as alternate career opportunities. The training program is designed to ensure that our trainees are fully equipped to meet the challenges required to succeed in any professional environment be it academics or alternate career paths in which their scientific training can be fully utilized.

Public Health Relevance

Research into both animal and human reproductive biology has widespread implications for human health. By establishing a new and innovative Reproductive and Developmental Sciences Training Program (RDSTP), we will train young scientists to have the ability to succeed and establish careers critical to research priorities established for the reproductive sciences as well as alternate careers that will enhance the field.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Institutional National Research Service Award (T32)
Project #
3T32HD087166-01S1
Application #
9386337
Study Section
Program Officer
Taymans, Susan
Project Start
2016-05-01
Project End
2021-04-30
Budget Start
2016-12-01
Budget End
2017-04-30
Support Year
1
Fiscal Year
2017
Total Cost
$4,814
Indirect Cost
$357
Name
Michigan State University
Department
Veterinary Sciences
Type
Schools of Earth Sciences/Natur
DUNS #
193247145
City
East Lansing
State
MI
Country
United States
Zip Code
48824
Ruebel, Meghan L; Schall, Peter Z; Midic, Uros et al. (2018) Transcriptome analysis of rhesus monkey failed-to-mature oocytes: deficiencies in transcriptional regulation and cytoplasmic maturation of the oocyte mRNA population. Mol Hum Reprod 24:478-494
Severance, Ashley L; Latham, Keith E (2018) Meeting the meiotic challenge: Specializations in mammalian oocyte spindle formation. Mol Reprod Dev 85:178-187
Smith, Arianna; Witte, Elizabeth; McGee, Devin et al. (2017) Cortisol inhibits CSF2 and CSF3 via DNA methylation and inhibits invasion in first-trimester trophoblast cells. Am J Reprod Immunol 78:
Severance, Ashley L; Latham, Keith E (2017) PLK1 regulates spindle association of phosphorylated eukaryotic translation initiation factor 4E-binding protein and spindle function in mouse oocytes. Am J Physiol Cell Physiol 313:C501-C515
McGee, Devin; Smith, Arianna; Poncil, Sharra et al. (2017) Cervical HSV-2 infection causes cervical remodeling and increases risk for ascending infection and preterm birth. PLoS One 12:e0188645
Ruebel, Meghan L; Cotter, Matthew; Sims, Clark R et al. (2017) Obesity Modulates Inflammation and Lipid Metabolism Oocyte Gene Expression: A Single-Cell Transcriptome Perspective. J Clin Endocrinol Metab 102:2029-2038