Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007600-02
Application #
3541387
Study Section
Research Manpower Review Committee (MR)
Project Start
1985-07-15
Project End
1989-06-30
Budget Start
1987-07-01
Budget End
1988-06-30
Support Year
2
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Masonic Medical Research Laboratory, Inc
Department
Type
DUNS #
077307437
City
Utica
State
NY
Country
United States
Zip Code
13501
Antzelevitch, C; Sicouri, S; Litovsky, S H et al. (1991) Heterogeneity within the ventricular wall. Electrophysiology and pharmacology of epicardial, endocardial, and M cells. Circ Res 69:1427-49
Sicouri, S; Antzelevitch, C (1991) A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle. The M cell. Circ Res 68:1729-41
Krishnan, S C; Antzelevitch, C (1991) Sodium channel block produces opposite electrophysiological effects in canine ventricular epicardium and endocardium. Circ Res 69:277-91
Sicouri, S; Antzelevitch, C (1991) Afterdepolarizations and triggered activity develop in a select population of cells (M cells) in canine ventricular myocardium: the effects of acetylstrophanthidin and Bay K 8644. Pacing Clin Electrophysiol 14:1714-20
Litovsky, S H; Antzelevitch, C (1990) Differences in the electrophysiological response of canine ventricular subendocardium and subepicardium to acetylcholine and isoproterenol. A direct effect of acetylcholine in ventricular myocardium. Circ Res 67:615-27
Davidenko, J M; Cohen, L; Goodrow, R et al. (1989) Quinidine-induced action potential prolongation, early afterdepolarizations, and triggered activity in canine Purkinje fibers. Effects of stimulation rate, potassium, and magnesium. Circulation 79:674-86
Litovsky, S H; Antzelevitch, C (1989) Rate dependence of action potential duration and refractoriness in canine ventricular endocardium differs from that of epicardium: role of the transient outward current. J Am Coll Cardiol 14:1053-66