This revised application requests support for an interdisciplinary training program in cardiovascular behavioral medicine. The focal point of the program is the basic and/or clinical research training of predoctoral students and postdoctoral fellows around two programmatic themes: risk factors and prevention, and cardiac pathophysiology. This program builds on, and will become a part of a successful, longstanding, and widely recognized graduate research training program in Medical Psychology/Behavioral Medicine at the Uniformed Services University. Students in the proposed training program will receive a strong foundation in areas of behavioral science, cardiac physiology, and cardiovascular behavioral medicine that will have an important impact on improving cardiovascular health outcomes and reducing health disparities. All program faculty members have strong, well-established research programs, track records of significant multi-disciplinary research collaboration, and substantial commitments to biomedical and behavioral research training relevant to cardiovascular disease. Primary training for the pre-doctoral students in this program occurs in the research environment. This is richly supplemented with a formal educational curriculum that has trained outstanding graduate students and fellows for over twenty years. The postdoctoral program is also based on a research apprenticeship model. Journal clubs, seminars, and conferences will significantly contribute to the social and intellectual interactions of the trainees and faculty. The present focus on interdisciplinary training meets a need identified by the NHLBI (NHLBI Task Force on Behavioral Research on Cardiovascular Lung and Blood Disease, 1998). To ensure interdisciplinary preparation, this program will uniquely provide trainees with a strong background in basic biobehavioral methods and laboratory techniques, as well as clinical applications and interventions. This will prepare trainees to be leading biobehavioral investigators who are equipped to study the role of behavior in disease outcomes, to understand the social, behavioral, and biological bases of health disparities, and thereby help reduce cardiovascular morbidity and mortality.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL069751-04
Application #
7059313
Study Section
Special Emphasis Panel (ZHL1-CSR-M (F1))
Program Officer
Jobe, Jared B
Project Start
2003-07-01
Project End
2008-06-30
Budget Start
2006-07-01
Budget End
2007-06-30
Support Year
4
Fiscal Year
2006
Total Cost
$264,041
Indirect Cost
Name
Henry M. Jackson Fdn for the Adv Mil/Med
Department
Type
DUNS #
144676566
City
Bethesda
State
MD
Country
United States
Zip Code
20817
Mehta, Puja K; Hermel, Melody; Nelson, Michael D et al. (2018) Mental stress peripheral vascular reactivity is elevated in women with coronary vascular dysfunction: Results from the NHLBI-sponsored Cardiac Autonomic Nervous System (CANS) study. Int J Cardiol 251:8-13
Sharma, Shilpa; Mehta, Puja K; Arsanjani, Reza et al. (2018) False-positive stress testing: Does endothelial vascular dysfunction contribute to ST-segment depression in women? A pilot study. Clin Cardiol 41:1044-1048
Wei, Janet; Bakir, May; Darounian, Navid et al. (2018) Myocardial Scar Is Prevalent and Associated With Subclinical Myocardial Dysfunction in Women With Suspected Ischemia But No Obstructive Coronary Artery Disease: From the Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction Study. Circulation 137:874-876
Elboudwarej, Omeed; Wei, Janet; Darouian, Navid et al. (2018) Maladaptive left ventricular remodeling in women: An analysis from the Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction study. Int J Cardiol 268:230-235
Humphries, K H; Izadnegahdar, M; Sedlak, T et al. (2017) Sex differences in cardiovascular disease - Impact on care and outcomes. Front Neuroendocrinol 46:46-70
Rambarat, Cecil A; Elgendy, Islam Y; Johnson, B Delia et al. (2017) Migraine Headache and Long-Term Cardiovascular Outcomes: An Extended Follow-Up of the Women's Ischemia Syndrome Evaluation. Am J Med 130:738-743
Kenkre, Tanya S; Malhotra, Pankaj; Johnson, B Delia et al. (2017) Ten-Year Mortality in the WISE Study (Women's Ischemia Syndrome Evaluation). Circ Cardiovasc Qual Outcomes 10:
Eastwood, Jo-Ann; Taylor, Doris A; Johnson, B Delia et al. (2017) Premature atherosclerosis in premenopausal women: Does cytokine balance play a role? Med Hypotheses 109:38-41
Landes, Sofy; Dela Cruz, Sherwin; Wei, Janet et al. (2017) Cold Pressor Stress Cardiac Magnetic Resonance Myocardial Flow Reserve Is Not Useful for Detection of Coronary Endothelial Dysfunction in Women with Signs and Symptoms of Ischemia and No Obstructive CAD. PLoS One 12:e0169818
Wei, Janet; Minissian, Margo; Bairey Merz, C Noel (2016) Pregnancy outcomes, reproductive history and cardiovascular disease risk in women: What do we know and what is needed? Eur J Prev Cardiol 23:1860-1862

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