This is a five-year competitive renewal that requests support for a multidisciplinary post-doctoral research training program aimed at preparing physicians and other scientists for independent careers in the investigation of childhood neuropsychiatric disorders. Such programs are urgently needed. This need is based on the large number of children affected with neuropsychiatric disorders, the considerable costs to society associated with their care, the limited effectiveness of available treatment and prevention programs, the small number of investigators active in the field, and the potential for significant scientific advances in the foreseeable future. There are two major components to this training: (1) a mentor-based research training that brings together established investigators in child psychiatry, child psychology, neuropsychology, pediatrics, epidemiology, genetics, molecular and developmental neurobiology, in vivo neuroimaging, neuropsychopharmacology and efficacy and services research with an outstanding group of post-doctoral fellows from a broad range of scientific backgrounds; and (2) an individually tailored core curriculum that focuses on the skills necessary to achieve the status of an independent investigator. This curriculum includes formal training in research design and biostatistics; critical appraisal of the scientific literature; mastery of the knowledge base concerning neuropsychiatric disorders of childhood onset; formulation of research questions, grant preparation and project management; and sensitivity to a range of issues concerning the protection of human subjects and ethical conduct of science. Evidence of the program's accomplishments include the success that recent graduates from the training program have had in receiving career development awards from NIH or private foundations as well as R01 grant support, NARSAD Young Investigator Awards, or other independent grant support. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Institutional National Research Service Award (T32)
Project #
5T32MH018268-22
Application #
7107184
Study Section
Special Emphasis Panel (ZMH1-ERB-X (02))
Program Officer
Boyce, Cheryl A
Project Start
1985-07-01
Project End
2010-06-30
Budget Start
2006-07-01
Budget End
2007-06-30
Support Year
22
Fiscal Year
2006
Total Cost
$381,159
Indirect Cost
Name
Yale University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Taylor, Jerome H; Lebowitz, Eli R; Jakubovski, Ewgeni et al. (2018) Monotherapy Insufficient in Severe Anxiety? Predictors and Moderators in the Child/Adolescent Anxiety Multimodal Study. J Clin Child Adolesc Psychol 47:266-281
Wu, Jia; Willner, Cynthia J; Hill, Claire et al. (2018) Emotional eating and instructed food-cue processing in adolescents: An ERP study. Biol Psychol 132:27-36
Morie, Kristen P; Wu, Jia; Landi, Nicole et al. (2018) Feedback processing in adolescents with prenatal cocaine exposure: an electrophysiological investigation. Dev Neuropsychol 43:183-197
Jackson, Scott L J; Hart, Logan; Brown, Jane Thierfeld et al. (2018) Brief Report: Self-Reported Academic, Social, and Mental Health Experiences of Post-Secondary Students with Autism Spectrum Disorder. J Autism Dev Disord 48:643-650
Cho, Youngsun T; Lam, Norman H; Starc, Martina et al. (2018) Effects of reward on spatial working memory in schizophrenia. J Abnorm Psychol 127:695-709
Dvornek, Nicha C; Ventola, Pamela; Duncan, James S (2018) COMBINING PHENOTYPIC AND RESTING-STATE FMRI DATA FOR AUTISM CLASSIFICATION WITH RECURRENT NEURAL NETWORKS. Proc IEEE Int Symp Biomed Imaging 2018:725-728
Taylor, Jerome H; Landeros-Weisenberger, Angeli; Coughlin, Catherine et al. (2018) Ketamine for Social Anxiety Disorder: A Randomized, Placebo-Controlled Crossover Trial. Neuropsychopharmacology 43:325-333
Morie, Kristen P; Yip, Sarah W; Zhai, Zu Wei et al. (2017) White-matter crossing-fiber microstructure in adolescents prenatally exposed to cocaine. Drug Alcohol Depend 174:23-29
Rutherford, Helena J V; Maupin, Angela N; Landi, Nicole et al. (2017) Parental reflective functioning and the neural correlates of processing infant affective cues. Soc Neurosci 12:519-529
Taylor, J H; Xu, Y; Li, F et al. (2017) Psychosocial predictors and moderators of weight management programme outcomes in ethnically diverse obese youth. Pediatr Obes 12:453-461

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