This is a proposal to continue a Training Program in Neuroimaging to train basic researchers and physician scientists in the scientific aspects of neuroimaging. The breadth of the program encompasses neuroimaging in all biobehavioral sciences from molecular probes to clinical psychiatry, while at the same time providing in depth focus on the theory and practice of neuroimaging strategy, physics, instrumentation and application.
The specific aims of this program are: 1) to provide trainees with the skills necessary to conduct neuroimaging research studies of brain structure and function in experimental animal and human models; 2) to provide trainees with a comprehensive understanding of the use of neuroimaging techniques from wet bench procedures such as optical intrinsic signal imaging to tomographic methods like MR and PET; 3) to provide trainees with the knowledge necessary for research design, statistical analysis and interpretation of different types of imaging data; 4) to prepare trainees to establish their own laboratories and independent academic research careers in neuroimaging. This program includes didactic course work with hands- on experience in several laboratories, culminating in a focused research project. The emphasis of this training program is on the basic science of neuroimaging and the use of neuroimaging in the pursuit of basic neurobiological results. This training program in neuroimaging is needed to address the national demand for research on mapping the brain. UCLA has the range of capabilities and depth of investigator knowledge necessary to maintain a focused program devoted to neuroimaging. We have the laboratory resources, faculty interest and expertise needed to run training program of this breadth and depth.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Institutional National Research Service Award (T32)
Project #
5T32MH019950-06
Application #
6391569
Study Section
Special Emphasis Panel (ZMH1-NRB-A (01))
Program Officer
Goldschmidts, Walter L
Project Start
1996-07-01
Project End
2004-06-30
Budget Start
2001-07-01
Budget End
2002-06-30
Support Year
6
Fiscal Year
2001
Total Cost
$172,120
Indirect Cost
Name
University of California Los Angeles
Department
Neurology
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Jung, Brian C; Choi, Soo I; Du, Annie X et al. (2012) MRI shows a region-specific pattern of atrophy in spinocerebellar ataxia type 2. Cerebellum 11:272-9
Jung, Brian C; Choi, Soo I; Du, Annie X et al. (2012) Principal component analysis of cerebellar shape on MRI separates SCA types 2 and 6 into two archetypal modes of degeneration. Cerebellum 11:887-95
Ying, S H; Choi, S I; Perlman, S L et al. (2006) Pontine and cerebellar atrophy correlate with clinical disability in SCA2. Neurology 66:424-6
Taylor, Janelle L; Blanton, Rebecca E; Levitt, Jennifer G et al. (2005) Superior temporal gyrus differences in childhood-onset schizophrenia. Schizophr Res 73:235-41
Marquardt, Renee K; Levitt, Jennifer G; Blanton, Rebecca E et al. (2005) Abnormal development of the anterior cingulate in childhood-onset schizophrenia: a preliminary quantitative MRI study. Psychiatry Res 138:221-33
Ying, S H; Choi, S I; Lee, M et al. (2005) Relative atrophy of the flocculus and ocular motor dysfunction in SCA2 and SCA6. Ann N Y Acad Sci 1039:430-5
Blanton, Rebecca E; Levitt, Jennifer G; Peterson, Jeffrey R et al. (2004) Gender differences in the left inferior frontal gyrus in normal children. Neuroimage 22:626-36