The overall goal of this funding is to recruit and support the research training of outstanding graduate veterinarians. By so doing we will address the national need posed by the shortage of veterinarians with contemporary research training. The UW-Madison School of Veterinary Medicine is well positioned to address this need as a result of its: 1) multidisciplinary research training program (Comparative Biomedical Sciences PhD program) with major strengths in Infectious Disease &Immunology, and Cellular &Molecular Regulation of Physiological Processes;2) outstanding roster of 24 Trainers who in aggregate have more than $15,000,000 in extramural funding and a record of commitment to research training;3) campus culture that fosters collaborative research and graduate student training;4) long standing record of providing research training to veterinarians;5) outstanding facilities and cutting edge support services;6) strong research ethics and professional skills course;and 7) commitment to minority student recruitment. We request funds for four Trainees for a 5 year period. Trainees will be supported for up to 3 years, during which time they will concurrently fulfill the requirements of the Comparative Biomedical Sciences PhD Program.
The Specific Aims of the training program are: 1) Provide veterinarians with contemporary problem solving and laboratory skills required to address national needs in translational biomedical research;and 2) Increase the number of veterinarians who serve as mentors for veterinary medical students considering a career in research. Subsidiary goals include: 1) Recruit veterinary medical students to pursue the DVM at the UW-Madison and participate in our portfolio of research training programs (Merial, T35, one year T32, Postdoctoral T32);2) Increase the number of underrepresented minority students pursuing research training at UW-Madison;3) Provide participating students with training in research ethics, responsible conduct of research and professional skills for successful careers in research.

Public Health Relevance

There is critical need to increase the pool of veterinarians with contemporary research training. The proposed program will address this need by supporting the research training of 4 outstanding veterinarians by a team of 24 well-funded faculty with strong graduate student training records. This will be conducted in an outstanding environment with exceptional resources, at a campus with a historical commitment to graduate student research training.

Agency
National Institute of Health (NIH)
Institute
Office of The Director, National Institutes of Health (OD)
Type
Institutional National Research Service Award (T32)
Project #
5T32OD010423-08
Application #
8690986
Study Section
Comparative Medicine Review Committee (RIRG)
Program Officer
Moro, Manuel H
Project Start
2007-07-01
Project End
2017-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
8
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Pathology
Type
Schools of Veterinary Medicine
DUNS #
City
Madison
State
WI
Country
United States
Zip Code
53715
Hillers, Lauren E; D'Amato, Joseph V; Chamberlin, Tamara et al. (2018) Obesity-Activated Adipose-Derived Stromal Cells Promote Breast Cancer Growth and Invasion. Neoplasia 20:1161-1174
Verant, Michelle L; Bohuski, Elizabeth A; Richgels, Katherine L D et al. (2018) Determinants of Pseudogymnoascus destructans within bat hibernacula: implications for surveillance and management of white-nose syndrome. J Appl Ecol 55:820-829
Reinhart, J M; Ekena, J; Cioffi, A C et al. (2018) A single-nucleotide polymorphism in the canine cytochrome b5 reductase (CYB5R3) gene is associated with sulfonamide hypersensitivity and is overrepresented in Doberman Pinschers. J Vet Pharmacol Ther 41:402-408
Reinhart, Jennifer M; Rose, Warren; Panyard, Daniel J et al. (2018) RNA expression profiling in sulfamethoxazole-treated patients with a range of in vitro lymphocyte cytotoxicity phenotypes. Pharmacol Res Perspect 6:e00388
Chamberlin, Tamara; D'Amato, Joseph V; Arendt, Lisa M (2017) Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity. Breast Cancer Res 19:128
Stading, Ben; Ellison, James A; Carson, William C et al. (2017) Protection of bats (Eptesicus fuscus) against rabies following topical or oronasal exposure to a recombinant raccoon poxvirus vaccine. PLoS Negl Trop Dis 11:e0005958
Amene, E; Horn, B; Pirie, R et al. (2016) Filling gaps in notification data: a model-based approach applied to travel related campylobacteriosis cases in New Zealand. BMC Infect Dis 16:475
Wong, Yat Yee; Rakasz, Eva G; Gasper, David J et al. (2016) Immunogenicity of trimethoprim/sulfamethoxazole in a macaque model of HIV infection. Toxicology 368-369:10-18
Baan, Mieke; Krentz, Kathleen J; Fontaine, Danielle A et al. (2016) Successful in vitro fertilization and generation of transgenics in Black and Tan Brachyury (BTBR) mice. Transgenic Res 25:847-854
Tisoncik-Go, Jennifer; Gasper, David J; Kyle, Jennifer E et al. (2016) Integrated Omics Analysis of Pathogenic Host Responses during Pandemic H1N1 Influenza Virus Infection: The Crucial Role of Lipid Metabolism. Cell Host Microbe 19:254-66

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