The goal of this project is to increase minority participation in biomedical research through an educational and research program that is formulated to assist minority serving institutions establishing bioinformatics programs ranging in size from a single course to a degree program. We will assist five primary partners that have established a sequence based bioinformatics course in developing a more extensive bioinformatics program consisting of multiple courses, degrees/certificates, publications and grant support. In addition, we will continue to assist in establishing initial courses with a rotating series of informal partners. We will also enhance our support with an online, educational computational center and learning environment. This center will facilitate educational initiatives with a stand-alone streaming set of multimedia modules covering critical bioinformatics concepts ranging from basic biology to advanced bioinformatics topics to applying bioinformatics software in optimal ways. In addition, the center will serve as a self paced interdisciplinary bioinformatics resource for students and faculty at minority serving institutions enabling bioinformatics resources to be accessed through an environment that provides educational support. Specifically we will achieve this goal through a four component program that includes: 1) Improving the curriculum at minority serving institutions by adding bioinformatics components into multiple courses and in multiple departments, and integrating bioinformatics into research projects. 2) A summer institute which trains faculty from minority serving institutions in bioinformatics teaching and research techniques. 3) An Online Educational Center and learning environment featuring online interdisciplinary teaching resources supplemented with multimedia modules, bioinformatics software and problem sets. 4) An eight week research internship focused on publishable research results. This four component program assists minority serving institutions by embedding aspects of bioinformatics into a broad swath of scientific disciplines in both coursework and research activities.

Public Health Relevance

This project assists minority scientists in making their research more effective and efficient by training them to make use of modern bioinformatics techniques to exploit the large amount of sequence, genomics, and protein structural data being generated in biomedical research.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
MARC Ancillary Training Activities (Grant) (NIGMS) (T36)
Project #
5T36GM095335-04
Application #
8610323
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Sesma, Michael A
Project Start
2011-02-01
Project End
2016-01-31
Budget Start
2014-02-01
Budget End
2015-01-31
Support Year
4
Fiscal Year
2014
Total Cost
$667,742
Indirect Cost
$27,706
Name
Carnegie-Mellon University
Department
Biostatistics & Other Math Sci
Type
Schools of Arts and Sciences
DUNS #
052184116
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Isaza, Clara; Rosas, Juan F; Lorenzo, Enery et al. (2018) Biological signaling pathways and potential mathematical network representations: biological discovery through optimization. Cancer Med 7:1875-1895
González De León, Joenice; González Méndez, Ricardo; Cadilla, Carmen L et al. (2018) Identification of Immunoglobulin E-Binding Proteins of the Xerophilic Fungus Aspergillus penicillioides Crude Mycelial Mat Extract and Serological Reactivity Assessment in Subjects with Different Allergen Reactivity Profiles. Int Arch Allergy Immunol 175:147-159
Clark, Louis; Leatherby, Danielle; Krilich, Elizabeth et al. (2018) In silico analysis of class I adenylate-forming enzymes reveals family and group-specific conservations. PLoS One 13:e0203218
Montes-Rodríguez, Ingrid M; Rodríguez-Pou, Yesenia; González-Méndez, Ricardo R et al. (2018) Characterization of Histone Genes from the Bivalve Lucina Pectinata. Int J Environ Res Public Health 15:
Cruz-Rivera, Yazeli E; Perez-Morales, Jaileene; Santiago, Yaritza M et al. (2018) A Selection of Important Genes and Their Correlated Behavior in Alzheimer's Disease. J Alzheimers Dis 65:193-205
Martinez, Teresa; Martinez, Idali; Vazquez, Guillermo J et al. (2016) Genetic environment of the KPC gene in Acinetobacter baumannii ST2 clone from Puerto Rico and genomic insights into its drug resistance. J Med Microbiol 65:784-92
Padín-Irizarry, Vivian; Colón-Lorenzo, Emilee E; Vega-Rodríguez, Joel et al. (2016) Glutathione-deficient Plasmodium berghei parasites exhibit growth delay and nuclear DNA damage. Free Radic Biol Med 95:43-54
Rodriguez, Yacidzohara; Gonzalez-Mendez, Ricardo R; Cadilla, Carmen L (2016) Evolution of the Twist Subfamily Vertebrate Proteins: Discovery of a Signature Motif and Origin of the Twist1 Glycine-Rich Motifs in the Amino-Terminus Disordered Domain. PLoS One 11:e0161029
Arbelo-Lopez, Hector D; Simakov, Nikolay A; Smith, Jeremy C et al. (2016) Homolytic Cleavage of Both Heme-Bound Hydrogen Peroxide and Hydrogen Sulfide Leads to the Formation of Sulfheme. J Phys Chem B 120:7319-31
Martínez, Teresa; Ropelewski, Alexander J; González-Mendez, Ricardo et al. (2016) Draft Genome Sequence of a Multidrug-Resistant Klebsiella pneumoniae Carbapenemase-Producing Acinetobacter baumannii Sequence Type 2 Isolate from Puerto Rico. Genome Announc 4:

Showing the most recent 10 out of 27 publications