The Indiana Clinical and Translational Sciences Institute (CTSI) was created in 2008 at the crest of a wave of transformation of ttie three research universities in Indiana and has become a flagship catalyst for the state's biomedical initiatives. The mission of the Indiana CTSI is to be an integrated home for clinical and translational research that creates a shared, investigator-friendly institutional environment and provides easily accessible resources, services, and training td conduct the highest-quality research dedicated to improving human health across Indiana and beyond. The Four Specific Aims of the Indiana CTSI are:
Aim I. Implement an Indiana roadmap for building,the ideal research environment and collaborative platforms to conduct innovative research using our excellent multi-institutional, public-private partnerships throughout the state of Indiana and beyond by bringing together all three major research universities, Indiana, Purdue and Notre Dame, the state's key health care provider partners, private sector and corporate entities, and local and state agencies to create the infrastructure.
Aim II. Further develop our successful Indiana CTSI established with the previous award into an integrated home that supports the careers and research projects of translational scientists and trainees through a streamlined structure, empowered leadership and administration, coordinated partner institution resources, robust informatics infrastructure, innovative project development teams, and continuous evaluation and process improvement.
Aim III. Promote utilization of our innovative services arjid a well-tested network of resources and technologies in order to catalyze high-quality, efficient, and safe clinical and translational research. We have created Project Assistance and Resources for Translational Scientists (PARTS) suite of both established and new research support services and resources, a statewide network of technology cores, and a coordinated human subject research services and facilities.
Aim I V. Extend our success in statewide education and training of clinical and translational research workforce th'rough our Career development, Education and Research Training (CERT) suite of programs that includes successful existing programs, new training programs, and novel educational tools.

Public Health Relevance

; The Indiana Clinical and Translational Sciences Institute (CTSI) was created in 2008 as a statewide institute by the partnership of three research universities in Indiana (Indiana, Purdue and Notre Dame) and has become an essential resource for the state's biomedical initiatives. Here we describe its innovative vision, its impact, and its success in creating public-private partnerships to benefit the health and economy of the state.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Training Award (TL1)
Project #
5TL1TR001107-05
Application #
9283644
Study Section
Special Emphasis Panel (ZAI1)
Program Officer
Hsiao, H Timothy
Project Start
2013-09-26
Project End
2018-09-30
Budget Start
2017-05-01
Budget End
2018-09-30
Support Year
5
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Psychiatry
Type
Schools of Medicine
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Klymenko, Yuliya; Wates, Rebecca B; Weiss-Bilka, Holly et al. (2018) Modeling the effect of ascites-induced compression on ovarian cancer multicellular aggregates. Dis Model Mech 11:
Riley, Timothy P; Hellman, Lance M; Gee, Marvin H et al. (2018) T cell receptor cross-reactivity expanded by dramatic peptide-MHC adaptability. Nat Chem Biol 14:934-942
Dahlgren, Paige N; Bishop, Kanokwan; Dey, Shatovisha et al. (2018) Development of a New Monochrome Multiplex qPCR Method for Relative Telomere Length Measurement in Cancer. Neoplasia 20:425-431
Castellanos, Irina; Kronenberger, William G; Pisoni, David B (2018) Psychosocial Outcomes in Long-Term Cochlear Implant Users. Ear Hear 39:527-539
Frump, Andrea L; Selej, Mona; Wood, Jordan A et al. (2018) Hypoxia Upregulates Estrogen Receptor ? in Pulmonary Artery Endothelial Cells in a HIF-1?-Dependent Manner. Am J Respir Cell Mol Biol 59:114-126
Hunter, Cynthia R; Pisoni, David B (2018) Extrinsic Cognitive Load Impairs Spoken Word Recognition in High- and Low-Predictability Sentences. Ear Hear 39:378-389
Nagayasu, Eiji; Hwang, Yu-Chen; Liu, Jun et al. (2017) Loss of a doublecortin (DCX)-domain protein causes structural defects in a tubulin-based organelle of Toxoplasma gondii and impairs host-cell invasion. Mol Biol Cell 28:411-428
Marussich, Lauren; Lu, Kun-Han; Wen, Haiguang et al. (2017) Mapping white-matter functional organization at rest and during naturalistic visual perception. Neuroimage 146:1128-1141
Brown, Ellen R; Lu, Yvonne; Beaven, Joyce et al. (2017) Engagement and Quality of Life in Under-represented Older Adults: A Community-Based Participatory Research Project. Narrat Inq Bioeth 7:E7-E9
Hunter, Cynthia R; Kronenberger, William G; Castellanos, Irina et al. (2017) Early Postimplant Speech Perception and Language Skills Predict Long-Term Language and Neurocognitive Outcomes Following Pediatric Cochlear Implantation. J Speech Lang Hear Res 60:2321-2336

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