Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project--Cooperative Agreements (U01)
Project #
1U01AI033355-01
Application #
3548052
Study Section
Special Emphasis Panel (SRC (58))
Project Start
1992-09-01
Project End
1995-08-31
Budget Start
1992-09-01
Budget End
1993-08-31
Support Year
1
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Woffendin, C; Ranga, U; Yang, Z et al. (1996) Expression of a protective gene-prolongs survival of T cells in human immunodeficiency virus-infected patients. Proc Natl Acad Sci U S A 93:2889-94
Nabel, G J; Gordon, D; Bishop, D K et al. (1996) Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes. Proc Natl Acad Sci U S A 93:15388-93
Fox, B A; Woffendin, C; Yang, Z Y et al. (1995) Genetic modification of human peripheral blood lymphocytes with a transdominant negative form of Rev: safety and toxicity. Hum Gene Ther 6:997-1004
Muller, D W; Gordon, D; San, H et al. (1994) Catheter-mediated pulmonary vascular gene transfer and expression. Circ Res 75:1039-49
Woffendin, C; Yang, Z Y; Udaykumar et al. (1994) Nonviral and viral delivery of a human immunodeficiency virus protective gene into primary human T cells. Proc Natl Acad Sci U S A 91:11581-5
Poo, H; Fox, B A; Petty, H R (1994) Ligation of CD3 triggers transmembrane proximity between LFA-1 and cortical microfilaments in a cytotoxic T cell clone derived from tumor infiltrating lymphocytes: a quantitative resonance energy transfer microscopy study. J Cell Physiol 159:176-80
Ohno, T; Gordon, D; San, H et al. (1994) Gene therapy for vascular smooth muscle cell proliferation after arterial injury. Science 265:781-4
Nabel, E G; Yang, Z; Muller, D et al. (1994) Safety and toxicity of catheter gene delivery to the pulmonary vasculature in a patient with metastatic melanoma. Hum Gene Ther 5:1089-94
Nabel, G J; Nabel, E G; Yang, Z Y et al. (1993) Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans. Proc Natl Acad Sci U S A 90:11307-11