This application responds to the cooperative agreement of RFA 90-CA-05 of the National Collaborative Diagnostic Imaging Trial Project. The focus of the investigation is the development of specific decision algorithms for the appropriate, sequential use of state-of-the-art magnetic resonance (MR), computed tomography (CT) and scintigraphy for diagnostic staging and evaluation of musculoskeletal tumors. Data gathered from the three imaging procedures will be compared with resected tumor specimen or with multiple biopsies obtained from the tumor. Both gross and histologic correlation will be made. Sensitivity, specificity, and accuracy for location, size, and specific regions of anatomic involvement will be made for each of the three imaging modalities. Direct comparative study of the imaging modality with the pathologic specimen as well as ROC analysis of specific parameters will be made.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01CA054009-03
Application #
2095618
Study Section
Special Emphasis Panel (SRC (48))
Project Start
1991-09-30
Project End
1994-10-31
Budget Start
1993-08-01
Budget End
1994-10-31
Support Year
3
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Stanford University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305