Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01CA063812-03
Application #
2105907
Study Section
Special Emphasis Panel (SRC (72))
Project Start
1994-07-01
Project End
1998-06-30
Budget Start
1996-09-01
Budget End
1998-06-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Tufts University
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02111
Kim, Y I; Baik, H W; Fawaz, K et al. (2001) Effects of folate supplementation on two provisional molecular markers of colon cancer: a prospective, randomized trial. Am J Gastroenterol 96:184-95
Kim, Y I; Fawaz, K; Knox, T et al. (2001) Colonic mucosal concentrations of folate are accurately predicted by blood measurements of folate status among individuals ingesting physiologic quantities of folate. Cancer Epidemiol Biomarkers Prev 10:715-9
Song, J; Medline, A; Mason, J B et al. (2000) Effects of dietary folate on intestinal tumorigenesis in the apcMin mouse. Cancer Res 60:5434-40
Mason, J B; Kim, Y i (1999) Nutritional strategies in the prevention of colorectal cancer. Curr Gastroenterol Rep 1:341-53
Choi, S W; Stickel, F; Baik, H W et al. (1999) Chronic alcohol consumption induces genomic but not p53-specific DNA hypomethylation in rat colon. J Nutr 129:1945-50
Sohn, K J; Puchyr, M; Salomon, R N et al. (1999) The effect of dietary folate on Apc and p53 mutations in the dimethylhydrazine rat model of colorectal cancer. Carcinogenesis 20:2345-50
Choi, S W; Mason, J B (1998) Folate and colorectal carcinogenesis: is DNA repair the missing link? Am J Gastroenterol 93:2013-6
Mason, J B (1998) Folate and colon cancer: a fascinating puzzle we have yet to complete. Clin Nutr 17:41-3
Kim, Y I; Fawaz, K; Knox, T et al. (1998) Colonic mucosal concentrations of folate correlate well with blood measurements of folate status in persons with colorectal polyps. Am J Clin Nutr 68:866-72
Choi, S W; Kim, Y I; Weitzel, J N et al. (1998) Folate depletion impairs DNA excision repair in the colon of the rat. Gut 43:93-9

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