AdolescentBrainCognitiveDevelopment(ABCD)isthelargestlong-termstudyofbraindevelopmentandchild healthintheUnitedStates.TheABCDResearchConsortiumconsistsof21researchsitesacrossthecountry, aCoordinatingCenter,andaDataAnalysisandInformaticsResourceCenter.Initsfirstfiveyears,under RFA-DA-15-015,ABCDenrolledadiversesampleof11,8789-10yearoldsfromacrosstheconsortium,and willtracktheirbiologicalandbehavioraldevelopmentthroughadolescenceintoyoungadulthood. Allparticipantsreceivedacomprehensivebaselineassessment,includingstate-of-the-artbrainimaging, neuropsychologicaltesting,bioassays,carefulassessmentofsubstanceuse,mentalhealth,physicalhealth, andcultureandenvironment.Asimilardetailedassessmentrecursevery2years.Interimin-personannual interviewsandmid-yeartelephoneormobileappassessmentsproviderefinedtemporalresolutionof developmentalchangesandlifeeventsthatoccurovertimewithminimalburdentoparticipatingyouthand parents.Intensiveeffortsaremadetokeepthevastmajorityofparticipantsinvolvedwiththestudythrough adolescenceandbeyond,andretentionratesthusfarareveryhigh.Neuroimaginghasexpandedour understandingofbraindevelopmentfromchildhoodintoadulthood.Usingthisandothercutting-edge technologies,ABCDcandeterminehowdifferentkindsofyouthexperiences(suchassports,school involvement,extracurricularactivities,videogames,socialmedia,unhealthysleeppatterns,andvaping) interactwitheachotherandwithachild?schangingbiologytoaffectbraindevelopmentandsocial,behavioral, academic,health,andotheroutcomes. Data,securelyandprivatelysharedwiththescientificcommunity,willenableinvestigatorsto:(1)describe individualdevelopmentalpathwaysintermsofneural,cognitive,emotional,andacademicfunctioning,and influencingfactors;?(2)developnationalstandardsofhealthybraindevelopment;?(3)investigatetherolesand interactionofgenesandtheenvironmentondevelopment;?(4)examinehowphysicalactivity,sleep,screen time,sportsinjuries(includingtraumaticbraininjuries),andotherexperiencesinfluencebraindevelopment;?(5) determineandreplicatefactorsthatinfluencementalhealthfromchildhoodtoyoungadulthood;?(6) characterizerelationshipsbetweenmentalhealthandsubstanceuse;?and(7)specifyhowuseofsubstances suchascannabis,alcohol,tobacco,andcaffeineaffectsdevelopmentaloutcomes,andhowneural,cognitive, emotional,andenvironmentalfactorsinfluencetheriskforadolescentsubstanceuse.
The ABCD Study consortium uses multimodal brain imaging, cognitive and clinical assessments, bioassays, mobilemonitoring,andcarefulassessmentofsubstanceuse,environment,psychopathologicalsymptoms,and socialfunctioningin11,8789-10year-oldstobefollowedover10years,todeterminetheeffectsofsubstance use on adolescent brain and cognitive development. This ABCD Research Project Site will follow and assess participants enrolled in the study. These data will be shared with the scientific community to address a comprehensiverangeofquestionsconcerningyouthdevelopment.
| Wade, Natasha E; Wallace, Alexander L; Swartz, Ann M et al. (2018) Aerobic Fitness Level Moderates the Association Between Cannabis Use and Executive Functioning and Psychomotor Speed Following Abstinence in Adolescents and Young Adults. J Int Neuropsychol Soc :1-12 |
| Lisdahl, Krista M; Sher, Kenneth J; Conway, Kevin P et al. (2018) Adolescent brain cognitive development (ABCD) study: Overview of substance use assessment methods. Dev Cogn Neurosci 32:80-96 |
