Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project--Cooperative Agreements (U01)
Project #
3U01HD028882-01S1
Application #
3552641
Study Section
Special Emphasis Panel (SRC (09))
Project Start
1992-05-01
Project End
1997-04-30
Budget Start
1993-02-01
Budget End
1993-04-30
Support Year
1
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Manning, S M; Jennings, R; Madsen, J R (2000) Pathophysiology, prevention, and potential treatment of neural tube defects. Ment Retard Dev Disabil Res Rev 6:14-Jun
Greene, N D; Gerrelli, D; Van Straaten, H W et al. (1998) Abnormalities of floor plate, notochord and somite differentiation in the loop-tail (Lp) mouse: a model of severe neural tube defects. Mech Dev 73:59-72
Fleming, A; Copp, A J (1998) Embryonic folate metabolism and mouse neural tube defects. Science 280:2107-9
Copp, A J (1998) Prevention of neural tube defects: vitamins, enzymes and genes. Curr Opin Neurol 11:97-102
Gerrelli, D; Copp, A J (1997) Failure of neural tube closure in the loop-tail (Lp) mutant mouse: analysis of the embryonic mechanism. Brain Res Dev Brain Res 102:217-24
Greene, N D; Copp, A J (1997) Inositol prevents folate-resistant neural tube defects in the mouse. Nat Med 3:60-6
Hoyle, C; Henderson, D J; Matthews, D J et al. (1996) Transferrin and its receptor in the development of genetically determined neural tube defects in the mouse embryo. Dev Dyn 207:35-46
Peeters, M C; Shum, A S; Hekking, J W et al. (1996) Relationship between altered axial curvature and neural tube closure in normal and mutant (curly tail) mouse embryos. Anat Embryol (Berl) 193:123-30
Shum, A S; Copp, A J (1996) Regional differences in morphogenesis of the neuroepithelium suggest multiple mechanisms of spinal neurulation in the mouse. Anat Embryol (Berl) 194:65-73
Letts, V A; Schork, N J; Copp, A J et al. (1995) A curly-tail modifier locus, mct1, on mouse chromosome 17. Genomics 29:719-24

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