Multicenter Study of Hydroxyurea in Sickle Cell Anemia

Terrin, Michael L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project--Cooperative Agreements (U01)
• Project #: 5U01HL045696-05
• Application #: 2222398
• Study Section: Clinical Trials Review Committee (CLTR)
• Project Start: 1991-05-22
• Project End: 1997-04-30
• Budget Start: 1995-05-01
• Budget End: 1997-04-30
• Support Year: 5
• Fiscal Year: 1995

Institution

• Name: Maryland Medical Research Institute, Inc
• DUNS #: 069392181
• City: Baltimore
• State: MD
• Country: United States
• Zip Code: 21210

Publications

Ballas, Samir K; Bauserman, Robert L; McCarthy, William F et al. (2010) The impact of hydroxyurea on career and employment of patients with sickle cell anemia. J Natl Med Assoc 102:993-9

Ballas, Samir K; Bauserman, Robert L; McCarthy, William F et al. (2010) Hydroxyurea and acute painful crises in sickle cell anemia: effects on hospital length of stay and opioid utilization during hospitalization, outpatient acute care contacts, and at home. J Pain Symptom Manage 40:870-82

Ballas, Samir K; McCarthy, William F; Guo, Nan et al. (2010) Early detection of response to hydroxyurea therapy in patients with sickle cell anemia. Hemoglobin 34:424-9

Ballas, Samir K; Barton, Franca B; Waclawiw, Myron A et al. (2006) Hydroxyurea and sickle cell anemia: effect on quality of life. Health Qual Life Outcomes 4:59

Moore, R D; Charache, S; Terrin, M L et al. (2000) Cost-effectiveness of hydroxyurea in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia. Am J Hematol 64:26-31

Steinberg, M H; Lu, Z H; Nagel, R L et al. (1998) Hematological effects of atypical and Cameroon beta-globin gene haplotypes in adult sickle cell anemia. Am J Hematol 59:121-6

McMahon, R P; Waclawiw, M A; Geller, N L et al. (1997) An extension of stochastic curtailment for incompletely reported and classified recurrent events: the Multicenter Study of Hydroxyurea in Sickle Cell Anemia (MSH). Control Clin Trials 18:420-30

Steinberg, M H; Lu, Z H; Barton, F B et al. (1997) Fetal hemoglobin in sickle cell anemia: determinants of response to hydroxyurea. Multicenter Study of Hydroxyurea. Blood 89:1078-88

Charache, S (1997) Mechanism of action of hydroxyurea in the management of sickle cell anemia in adults. Semin Hematol 34:15-21

Charache, S; Barton, F B; Moore, R D et al. (1996) Hydroxyurea and sickle cell anemia. Clinical utility of a myelosuppressive ""switching"" agent. The Multicenter Study of Hydroxyurea in Sickle Cell Anemia. Medicine (Baltimore) 75:300-26