Novel Models of Cardiovascular Complications of Diabetes

Hsueh, Willa A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project--Cooperative Agreements (U01)
• Project #: 5U01HL070526-03
• Application #: 6653834
• Study Section: Special Emphasis Panel (ZDK1-GRB-4 (O2))
• Program Officer: Rabadan-Diehl, Cristina
• Project Start: 2001-09-30
• Project End: 2006-08-31
• Budget Start: 2003-09-01
• Budget End: 2004-08-31
• Support Year: 3
• Fiscal Year: 2003
• Total Cost: $762,500

Institution

• Name: University of California Los Angeles
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 092530369
• City: Los Angeles
• State: CA
• Country: United States
• Zip Code: 90095

Publications

Langfelder, Peter; Castellani, Lawrence W; Zhou, Zhiqiang et al. (2012) A systems genetic analysis of high density lipoprotein metabolism and network preservation across mouse models. Biochim Biophys Acta 1821:435-47

Collins, Alan R; Lyon, Christopher J; Xia, Xuefeng et al. (2009) Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genes. Circ Res 104:e42-54

Caglayan, Evren; Stauber, Bradley; Collins, Alan R et al. (2008) Differential roles of cardiomyocyte and macrophage peroxisome proliferator-activated receptor gamma in cardiac fibrosis. Diabetes 57:2470-9

Hsueh, Willa; Abel, E Dale; Breslow, Jan L et al. (2007) Recipes for creating animal models of diabetic cardiovascular disease. Circ Res 100:1415-27

Davis, Richard C; Jin, Angela; Rosales, Melenie et al. (2007) A genome-wide set of congenic mouse strains derived from CAST/Ei on a C57BL/6 background. Genomics 90:306-13

Drake, Thomas A; Schadt, Eric E; Lusis, Aldons J (2006) Integrating genetic and gene expression data: application to cardiovascular and metabolic traits in mice. Mamm Genome 17:466-79

Estrada-Smith, Daria; Collins, Alan R; Wang, Xuping et al. (2006) Impact of chromosome 2 obesity loci on cardiovascular complications of insulin resistance in LDL receptor-deficient C57BL/6 mice. Diabetes 55:2265-71

Ghazalpour, Anatole; Doss, Sudheer; Sheth, Sonal S et al. (2005) Genomic analysis of metabolic pathway gene expression in mice. Genome Biol 6:R59

Drake, Thomas A; Schadt, Eric E; Davis, Richard C et al. (2005) Integrating genetic and gene expression data to study the metabolic syndrome and diabetes in mice. Am J Ther 12:503-11

Davis, Richard C; Schadt, Eric E; Cervino, Alessandra C L et al. (2005) Ultrafine mapping of SNPs from mouse strains C57BL/6J, DBA/2J, and C57BLKS/J for loci contributing to diabetes and atherosclerosis susceptibility. Diabetes 54:1191-9