This application is to develop a community-linked collaboration in the District of Columbia (DC) to plan a multi-site, multi-level study to investigate disparities in maternal and child health and, ultimately, to improve major outcomes among inner city, high risk African American women and their children. The leading partners are Georgetown University (including a new Center on Health and Education, the Center for the Study of Learning, and the National Center for Education in Maternal and Child Health), MedStar Health (the corporate entity that delivers many babies for high risk, low income African American women), and the D.C. Developing Families Center (a comprehensive, inner city family center that integrates a nurse-midwife model with an Early HeadStart program and case management services). ? ? The specific aims in Phase 1 are: (1) to develop a strong community-university collaboration to design and implement clinical research (Phase 2) to reduce health disparities; (2) to conduct exploratory studies to inform decision-making for Phase 2; (3) to provide interdisciplinary research training opportunities for minority scientists and clinicians; (4) to work with NICHD staff and other Phase 1 projects in planning; and (5) to advance the methods and theories related to the key clinical outcomes of fetal loss, low birthweight, prematurity, neonatal and infant mortality, and early childhood morbidity. ? ? The Georgetown-DC collaborative team offers expertise in prenatal care, parenting, child neglect and abuse, maternal depression, maternal substance abuse and smoking, early intervention for at-risk children, maternal intellectual disabilities, intergenerational poverty, early childhood care and education, family functioning, welfare reform, health services models for inner city families, maternal infectious diseases, developmental neuroscience, and neuroimaging of young children's brains. Two sample studies are proposed, along with new methodologies, to investigate how the complex interactions among genetic, biological, behavioral, and environmental variables influence key health outcomes. ? ?
| Straub, Heather; Simon, Clarissa; Plunkett, Beth A et al. (2016) Evidence for a Complex Relationship Among Weight Retention, Cortisol and Breastfeeding in Postpartum Women. Matern Child Health J 20:1375-83 |
| O'Campo, Patricia; Schetter, Christine Dunkel; Guardino, Christine M et al. (2016) Explaining racial and ethnic inequalities in postpartum allostatic load: Results from a multisite study of low to middle income woment. SSM Popul Health 2:850-858 |
| Tanner Stapleton, Lynlee R; Dunkel Schetter, Christine; Dooley, Larissa N et al. (2016) The Community Child Health Network Life Stress Interview: a brief chronic stress measure for community health research. Anxiety Stress Coping 29:352-66 |
| McKinney, Chelsea O; Hahn-Holbrook, Jennifer; Chase-Lansdale, P Lindsay et al. (2016) Racial and Ethnic Differences in Breastfeeding. Pediatrics 138: |
| Schetter, Christine Dunkel; Saxbe, Darby; Cheadle, Alyssa et al. (2016) Postpartum Depressive Symptoms Following Consecutive Pregnancies: Stability, Change, and Mechanisms. Clin Psychol Sci 4:909-918 |
| Guardino, Christine M; Schetter, Christine Dunkel; Saxbe, Darby E et al. (2016) Diurnal salivary cortisol patterns prior to pregnancy predict infant birth weight. Health Psychol 35:625-33 |
| Simon, Clarissa D; Adam, Emma K; McKinney, Chelsea O et al. (2016) Breastfeeding, Bed-Sharing, and Maternal Cortisol. Clin Pediatr (Phila) 55:470-8 |
| Ramey, Sharon Landesman; Schafer, Peter; DeClerque, Julia L et al. (2015) The Preconception Stress and Resiliency Pathways Model: a multi-level framework on maternal, paternal, and child health disparities derived by community-based participatory research. Matern Child Health J 19:707-19 |
| Saxbe, Darby E; Adam, Emma K; Schetter, Christine Dunkel et al. (2015) Cortisol covariation within parents of young children: Moderation by relationship aggression. Psychoneuroendocrinology 62:121-8 |
| Endres, Loraine K; Straub, Heather; McKinney, Chelsea et al. (2015) Postpartum weight retention risk factors and relationship to obesity at 1 year. Obstet Gynecol 125:144-52 |
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