STDs and sexual network patterns have emerged as major proximate determinants of HIVtransmission among African Americans. Mounting evidence suggests that the convergence of structural and contextual factors, socio-cultural factors, and individual-level behaviors and risk factors, play a critical role in heterosexual HIV transmission among African American women. However, the dynamics of the relationship between these myriad factors remain unclear. This study will conduct a cross-sectional study of 500 African American women in two NorthCarolina counties with high rates of sexually transmitted diseases and HIV to examine risk factors for these infections. Specifically, we will determine the prevalence of Neisseriae gonorrhoeae (GC), Chlamydia trachomatis (CT), and HIV and estimate HIV incidence. In particular, we aim to increase our understanding of socio-cultural factors (for example, religiosity and spirituality) and proximate determinants (e.g., epidemiologic factors and high-risk sexual behaviors and practices, such as concurrent partnerships) that influence HIV/STI transmission and determine the strength of their association with GC, CT, and HIV infection. We will also conduct qualitative research through focus groups among 70-80 African American women to obtain more in- depth understanding of socio-cultural, structural, socioeconomic, and other contextual factorsthat influence HIV transmission among African American women in the study population; and behavioral and other proximate determinants identified as important in the cross-sectional study. Understanding these factors is a critical first step in designing effective HIV interventions for this population. Lay Language: This study is relevant to public health because it will examine risk factors for sexually transmitted diseases and HIV among African American women in two North Carolina counties with high rates of these infections. The goal of this study is to increase our understanding of how socio-cultural factors such as religion; socio- economic factors such as neighborhood poverty and racism; and other environmental factors such as a lack of recreation influence HIV transmission in this area.

Agency
National Institute of Health (NIH)
Institute
National Center for HIV, Viral Hepatitis, STDS and Tb Prevention (NCHHSTP)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01PS000094-03
Application #
7284242
Study Section
Special Emphasis Panel (ZPS1-SRC (99))
Project Start
2005-09-30
Project End
2009-09-29
Budget Start
2007-09-30
Budget End
2008-09-29
Support Year
3
Fiscal Year
2007
Total Cost
$207,292
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Ludema, Christina; Doherty, Irene A; White, Becky L et al. (2015) Characteristics of African American Women and Their Partners With Perceived Concurrent Partnerships in 4 Rural Counties in the Southeastern U.S. Sex Transm Dis 42:498-504
Ludema, Christina; Doherty, Irene A; White, Becky L et al. (2015) Religiosity, spirituality, and HIV risk behaviors among African American women from four rural counties in the southeastern U.S. J Health Care Poor Underserved 26:168-81
Adimora, Adaora A; Schoenbach, Victor J; Taylor, Eboni M et al. (2011) Concurrent partnerships, nonmonogamous partners, and substance use among women in the United States. Am J Public Health 101:128-36