Abstract

This will allow support for the cooperative Children's Cancer Study Group activities of Children' Memorial Hospital and its affilitates here in Chicago and in the suburbs of Downers Grove, Maywood, and Park Ridge, Illinois. Investigators at Children's Memorial hospital, during the past five years, have made significant contributions to the group. Scientific directions and leadership have been provided in the areas of the treatment of high risk acute lymphocytic leukemia, the treamtent of relapsing acute lymphocytic leukemia, the treatment of Wilm's tumor, and the investigation and use of Phase II new agents. Administrative direction and leadership have been given in the areas of participation in the group's executive committee, membership actions, and the use of computers with respect to both data management and administrative matters. The institution has participated in the group activities in a multidisciplinary fashion with attendance and participation in the areas of radiation therapy, diagostic imaging, immunology, nursing, data managment, neurosurgery, and pathology.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
2U10CA007431-26
Application #
3555888
Study Section
Cancer Clinical Investigation Review Committee (CCI)
Project Start
1978-12-01
Project End
1990-12-31
Budget Start
1988-12-01
Budget End
1989-12-31
Support Year
26
Fiscal Year
1989
Total Cost
Indirect Cost

  Institution

Name
Children's Memorial Hospital (Chicago)
Department
Type
DUNS #
City
Chicago
State
IL
Country
United States
Zip Code
60614

  Publications

Wacker, Pierre; Land, Vita J; Camitta, Bruce M et al. (2007) Allergic reactions to E. coli L-asparaginase do not affect outcome in childhood B-precursor acute lymphoblastic leukemia: a Children's Oncology Group Study. J Pediatr Hematol Oncol 29:627-32
Ravindranath, Y; Chang, M; Steuber, C P et al. (2005) Pediatric Oncology Group (POG) studies of acute myeloid leukemia (AML): a review of four consecutive childhood AML trials conducted between 1981 and 2000. Leukemia 19:2101-16
Shamberger, Robert C; LaQuaglia, Michael P; Gebhardt, Mark C et al. (2003) Ewing sarcoma/primitive neuroectodermal tumor of the chest wall: impact of initial versus delayed resection on tumor margins, survival, and use of radiation therapy. Ann Surg 238:563-7; discussion 567-8
Pollock, Brad H; Jenson, Hal B; Leach, Charles T et al. (2003) Risk factors for pediatric human immunodeficiency virus-related malignancy. JAMA 289:2393-9
Davies, Stella M; Bhatia, Smita; Ross, Julie A et al. (2002) Glutathione S-transferase genotypes, genetic susceptibility, and outcome of therapy in childhood acute lymphoblastic leukemia. Blood 100:67-71
Mitchell, Claudia; Fausto, Nelson (2002) Bone marrow-derived hepatocytes : rare but promising. Am J Pathol 161:349-50
Lacayo, N J; Lum, B L; Becton, D L et al. (2002) Pharmacokinetic interactions of cyclosporine with etoposide and mitoxantrone in children with acute myeloid leukemia. Leukemia 16:920-7
Ferguson, W S; Harris, M B; Goorin, A M et al. (2001) Presurgical window of carboplatin and surgery and multidrug chemotherapy for the treatment of newly diagnosed metastatic or unresectable osteosarcoma: Pediatric Oncology Group Trial. J Pediatr Hematol Oncol 23:340-8
Saylors 3rd, R L; Stine, K C; Sullivan, J et al. (2001) Cyclophosphamide plus topotecan in children with recurrent or refractory solid tumors: a Pediatric Oncology Group phase II study. J Clin Oncol 19:3463-9
Hurwitz, C A; Strauss, L C; Kepner, J et al. (2001) Paclitaxel for the treatment of progressive or recurrent childhood brain tumors: a pediatric oncology phase II study. J Pediatr Hematol Oncol 23:277-81

Showing the most recent 10 out of 24 publications