The mutually productive association of New York University with the Eastern Cooperative Oncology Group dates back to 1973. This has resulted in continued cross-fertilization of ideas and studies with other group members as well as interdisciplinary cooperation within the institution. Highlights of this involvement include leadership in specific protocols in hematologic neoplasias, melanoma, lung cancer, breast cancer, testicular cancer, head and neck cancer and colorectal cancer. In addition, New York University Cancer Center activities in new chemotherapeutic agents, biologic response modifiers and drug-radiation interaction are reflected in co-chairmenship of the New Drug and Pilot Studies Committee, and the Lung Cancer Committee as well as in vast numbers of groupwide and pilot studies utilizing these approaches. We propose to continue this close coordination between investigators in various therapeutic disciplines to bring about improved therapeutic strategies. Moreover, we predict that NYU will increase its group participation in other areas such as surgical oncology, gynecologic oncology, and radiation oncology as a result of additional recruitment into these multidisciplinary areas of the Cancer Center. This, as well as new involvement in epidemiology, chemoprevention, and cancer control are indicative of the broad commitment of NYU to the clinical research activities which fall within the scope of the Eastern Cooperative Oncology Group.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA016395-19
Application #
3556388
Study Section
Cancer Clinical Investigation Review Committee (CCI)
Project Start
1978-12-01
Project End
1994-06-30
Budget Start
1993-05-01
Budget End
1994-06-30
Support Year
19
Fiscal Year
1993
Total Cost
Indirect Cost
Name
New York University
Department
Type
Schools of Medicine
DUNS #
004514360
City
New York
State
NY
Country
United States
Zip Code
10012
Asbury, R F; Lipsitz, S; Graham, D et al. (2000) Treatment of squamous cell esophageal cancer with topotecan: an Eastern Cooperative Oncology Group Study (E2293). Am J Clin Oncol 23:45-6
Hochster, H S; Oken, M M; Winter, J N et al. (2000) Phase I study of fludarabine plus cyclophosphamide in patients with previously untreated low-grade lymphoma: results and and long-term follow-up--a report from the Eastern Cooperative Oncology Group. J Clin Oncol 18:987-94
Kucuk, O; Pandya, K J; Skeel, R T et al. (1999) Phase II study of cisplatin and 5-fluorouracil in previously treated metastatic breast cancer: an Eastern Cooperative Oncology Group study (PA 185). Breast Cancer Res Treat 57:201-6
Hochster, H; Strawderman, M H; Harris, J E et al. (1999) Conventional dose melphalan is inactive in metastatic melanoma: results of an Eastern Cooperative Oncology Group Study (E1687). Anticancer Drugs 10:245-8
Hochster, H; Oratz, R; Ettinger, D S et al. (1998) A phase II study of Didemnin B (NSC 325319) in advanced malignant melanoma: an Eastern Cooperative Oncology Group study (PB687). Invest New Drugs 16:259-63
Rosenthal, M A; Green, M; Wiernik, P et al. (1998) Epirubicin has modest single-agent activity in head and neck cancer but limited activity in metastatic melanoma and colorectal cancer: phase II studies by the Eastern Cooperative Oncology Group. Am J Clin Oncol 21:509-12
Chang, A Y; Tu, Z N; Smith, J L et al. (1995) Phase II trial of gallium nitrate, amonafide and teniposide in metastatic non-small cell lung cancer. An Eastern Cooperative Oncology Group study (E2588). Invest New Drugs 13:137-41
Witte, R S; Walsh, C; Fisher, H et al. (1992) Evaluation of deoxycoformycin in patients with advanced renal cell carcinoma. An ECOG pilot study. Invest New Drugs 10:49-50
Borden, E C; Kim, K; Ryan, L et al. (1992) Phase II trials of interferons-alpha and -beta in advanced sarcomas. J Interferon Res 12:455-8
Hochster, H S; Kim, K M; Green, M D et al. (1992) Activity of fludarabine in previously treated non-Hodgkin's low-grade lymphoma: results of an Eastern Cooperative Oncology Group study. J Clin Oncol 10:28-32

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