Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19CA100265-05
Application #
7737114
Study Section
Special Emphasis Panel (ZCA1-GRB-2 (O1))
Project Start
2008-03-21
Project End
2008-11-30
Budget Start
2008-03-21
Budget End
2008-11-30
Support Year
5
Fiscal Year
2008
Total Cost
$145,267
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
076580745
City
Boston
State
MA
Country
United States
Zip Code
02215
Davies, Jeff K; Brennan, Lisa L; Wingard, John R et al. (2018) Infusion of Alloanergized Donor Lymphocytes after CD34-selected Haploidentical Myeloablative Hematopoietic Stem Cell Transplantation. Clin Cancer Res 24:4098-4109
Barbon, C M; Davies, J K; Voskertchian, A et al. (2014) Alloanergization of human T cells results in expansion of alloantigen-specific CD8(+) CD28(-) suppressor cells. Am J Transplant 14:305-18
Hosing, Chitra; Kebriaei, Partow; Wierda, William et al. (2013) CARs in chronic lymphocytic leukemia -- ready to drive. Curr Hematol Malig Rep 8:60-70
Davies, Jeff K; Barbon, Christine M; Voskertchian, Annie et al. (2012) Ex vivo alloanergization with belatacept: a strategy to selectively modulate alloresponses after transplantation. Cell Transplant 21:2047-61
Singh, Harjeet; Figliola, Matthew J; Dawson, Margaret J et al. (2011) Reprogramming CD19-specific T cells with IL-21 signaling can improve adoptive immunotherapy of B-lineage malignancies. Cancer Res 71:3516-27
Ophir, Eran; Reisner, Yair (2009) Induction of tolerance in organ recipients by hematopoietic stem cell transplantation. Int Immunopharmacol 9:694-700
Davies, Jeffrey K; Nadler, Lee M; Guinan, Eva C (2009) Expansion of allospecific regulatory T cells after anergized, mismatched bone marrow transplantation. Sci Transl Med 1:1ra3
Davies, Jeffrey K; Yuk, Dongin; Nadler, Lee M et al. (2008) Induction of alloanergy in human donor T cells without loss of pathogen or tumor immunity. Transplantation 86:854-64
Haining, W Nicholas; Ebert, Benjamin L; Subrmanian, Aravind et al. (2008) Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells. J Immunol 181:1859-68
Parkman, Robertson (2008) Antigen-specific immunity following hematopoietic stem cell transplantation. Blood Cells Mol Dis 40:91-3

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