The goal of this proposal is to enable the Animal Disease Research Laboratory(ADRDL), South Dakota to serve as a whole genome sequencing laboratory for FDA CFSAN. ADRDL is one of the nationally preeminent full service, animal disease research and diagnostic laboratories that provides the fastest, most accurate, and most dependable animal disease diagnostic services possible. ADRDL is a not-for-profit lab and provides state-of-the-art diagnostic services and instrumentation for the detection of zoonotic and animal diseases and conducts over 500, 000 diagnostic tests every year. In this project, ADRDL will isolate and sequence genomes of 400 foodborne pathogens per year and perform bioinformatics analysis of the data and submit the metadata and raw data to NCBI sequence read archive.
Human infections caused by foodborne pathogens is a major health concern and cause several million dollars of burden to the United States economy. Whole genome sequencing is a powerful method to detect and track foodborne pathogens. In the proposed project, Animal Disease Research and Diagnostic Laboratory (ADRDL), South Dakota seeks to serve as a whole genome sequencing laboratory, sequence and analyze foodborne pathogen genomes for the Food and Drug Administration (FDA).
