Abstract

? Project Description: ? The RTOG recognizes the importance of a tissue resource of present and future correlative trials.
The specific aims of this tissue bank application are: ? (1) To acquire, store, and track blood, leukocytes and tissue samples from RTOG patients entered on Phase III clinical trials in compliance with policies and procedures of the Group Banking Committee of NCI. ? (2) To preserve the maximum amount of tissue in each sample by expert block, tissue array and sample preparation, by laser capture of appropriate tissue elements, and by appropriate tissue quality assurance. ? (3) To market, and distribute samples equitably to all qualified investigators by a standardized method developed or modified collaboratively with the Group Banking Committee of NCI. ? ?

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Resource-Related Research Projects--Cooperative Agreements (U24)
Project #
5U24CA114734-02
Application #
7122433
Study Section
Special Emphasis Panel (ZCA1-SRRB-3 (J1))
Program Officer
Lubensky, Irina
Project Start
2005-09-14
Project End
2010-03-31
Budget Start
2006-08-14
Budget End
2007-03-31
Support Year
2
Fiscal Year
2006
Total Cost
$801,045
Indirect Cost

  Institution

Name
American College of Radiology
Department
Type
DUNS #
062485800
City
Reston
State
VA
Country
United States
Zip Code
20191

  Publications

Lawrence, Yaacov R; Moughan, Jennifer; Magliocco, Anthony M et al. (2018) Expression of the DNA repair gene MLH1 correlates with survival in patients who have resected pancreatic cancer and have received adjuvant chemoradiation: NRG Oncology RTOG Study 9704. Cancer 124:491-498
Farrell, James J; Moughan, Jennifer; Wong, Jonathan L et al. (2016) Precision Medicine and Pancreatic Cancer: A Gemcitabine Pathway Approach. Pancreas 45:1485-1493
Li, Donghui; Moughan, Jennifer; Crane, Christopher et al. (2016) RECQ1 A159C Polymorphism Is Associated With Overall Survival of Patients With Resected Pancreatic Cancer: A Replication Study in NRG Oncology Radiation Therapy Oncology Group 9704. Int J Radiat Oncol Biol Phys 94:554-60
Ben-Josef, Edgar; George, Asha; Regine, William F et al. (2015) Glycogen Synthase Kinase 3 Beta Predicts Survival in Resected Adenocarcinoma of the Pancreas. Clin Cancer Res 21:5612-8
Rabinovitch, Rachel; Winter, Kathryn; Kuske, Robert et al. (2014) RTOG 95-17, a Phase II trial to evaluate brachytherapy as the sole method of radiation therapy for Stage I and II breast carcinoma--year-5 toxicity and cosmesis. Brachytherapy 13:17-22
Kunos, Charles A; Winter, Kathryn; Dicker, Adam P et al. (2013) Ribonucleotide reductase expression in cervical cancer: a radiation therapy oncology group translational science analysis. Int J Gynecol Cancer 23:615-21
Roach 3rd, Mack; Waldman, Fred; Pollack, Alan (2009) Predictive models in external beam radiotherapy for clinically localized prostate cancer. Cancer 115:3112-20
Woodward, Wendy A; Bristow, Robert G; Clarke, Michael F et al. (2009) Radiation Therapy Oncology Group translational research program stem cell symposium: incorporating stem cell hypotheses into clinical trials. Int J Radiat Oncol Biol Phys 74:1580-91