Abstract

We plan to provide fingerprint data for BAC clones covering the entire 3,000 Mb human genome in the next year; to use probes from 2/3 of the genome to position the fingerprint contigs onto chromosomes over the next 2 years; and to sequence 1/3 of the genome over the next 3 years. With contributions from other US and international labs, this should place more than 95 percent of the sequence in the public domain in 2001 for all to explore.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54HG002042-05
Application #
6623233
Study Section
Special Emphasis Panel (ZHG1-HGR-P (J2))
Program Officer
Felsenfeld, Adam
Project Start
1999-03-08
Project End
2004-10-31
Budget Start
2002-12-01
Budget End
2004-10-31
Support Year
5
Fiscal Year
2003
Total Cost
$48,871,087
Indirect Cost

  Institution

Name
Washington University
Department
Genetics
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Spieth, John; Lawson, Daniel; Davis, Paul et al. (2014) Overview of gene structure in C. elegans. WormBook :1-18
Ley, Timothy J; Mardis, Elaine R; Ding, Li et al. (2008) DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature 456:66-72
Huang, Xiaoqiu; Wang, Jianmin; Aluru, Srinivas et al. (2003) PCAP: a whole-genome assembly program. Genome Res 13:2164-70