This application describes plans to develop a collaborative partnership involving City College of New York and Memorial Sloan-Kettering Cancer Center. We propose to develop a Partnership that can take full advantage of CCNY's strengths as an institution of highly education for minority populations and the scientific and clinical resources of MSK, a major metropolitan cancer center. Our immediate goal is the establishment of joint projects in the areas of basic, behavioral and population sciences, with an emphasis on building capacity for collaboration. Specifically, in the first year, we propose a series of two pilot studies that will lead to competitive R01 proposals and that also serve as models fo future collaborative research efforts. A study of religious comforts and strains will help us to establish procedures for joint studi3es involving MSK cancer patients. A study of immunological functioning will demonstrate research projects as well as community interventions to promote cancer prevention and early detection. Research training experiences are incorporated in each of these joint pilot projects. Our plans address needs of minority students and scientists at critical junctures along the career development path. Our plans address needs of minority students and scientists at critical junctures along the career development path, including opportunities for CCNY students to work in Partnership projects and pursue special projects at MSK. Our longer- range goals include the development of joint post-doctoral fellowships as well as curricula in the advanced undergraduate/early graduate student level on the Biology of Cancer and Psychosocial Issues in Cancer Prevention, Control and Treatment. In the area of cancer outreach, we plan to bring together several of MSK's existing NCI-sponsored initiatives with CCNY's Continuing Education and campus health programs, to improve public understanding of cancer research, and to increase early detection and access to care in the Harlem community. Our partnership includes biological, behavioral and social scientists, clinical investigators and biomedical ethicists. Core members were selected to include specialists in areas relevant to the impact of cancer in minority communities, deans and area leaders with broad reach and awareness of faculty activities within their respective institutions, as well as scholars with experience in programs to mentor and train minority scientists.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Exploratory Grants--Cooperative Agreements (U56)
Project #
5U56CA096299-05
Application #
7075405
Study Section
Special Emphasis Panel (ZCA1-SRRB-7 (J1))
Program Officer
Aguila, H Nelson
Project Start
2002-06-13
Project End
2009-04-30
Budget Start
2006-06-01
Budget End
2009-04-30
Support Year
5
Fiscal Year
2006
Total Cost
$458,250
Indirect Cost
Name
City College of New York
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
603503991
City
New York
State
NY
Country
United States
Zip Code
10031
Zhong, Lina; Tu, Raymond; Gilchrist, M Lane (2013) Tether-supported biomembranes with ?-helical peptide-based anchoring constructs. Langmuir 29:299-307
Ziaei, Samira; Shimada, Naoko; Kucharavy, Herman et al. (2012) MNK1 expression increases during cellular senescence and modulates the subcellular localization of hnRNP A1. Exp Cell Res 318:500-8
Kovalovsky, Damian; Pezzano, Mark; Ortiz, Benjamin D et al. (2010) A novel TCR transgenic model reveals that negative selection involves an immediate, Bim-dependent pathway and a delayed, Bim-independent pathway. PLoS One 5:e8675
Osada, Masako; Jardine, Logan; Misir, Ruth et al. (2010) DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration. PLoS One 5:e9062
Shimada, Naoko; Rios, Ileana; Moran, Heriberto et al. (2009) p38 MAP kinase-dependent regulation of the expression level and subcellular distribution of heterogeneous nuclear ribonucleoprotein A1 and its involvement in cellular senescence in normal human fibroblasts. RNA Biol 6:293-304
Hwang, Bor-Jang; Kuttamperoor, Francis; Wu, Julia et al. (2009) Spectrum of mitochondrial DNA deletions within the common deletion region induced by low levels of UVB irradiation of human keratinocytes in vitro. Gene 440:23-7
Steinberg, Mark L; Hubbard, Karen; Utti, Charles et al. (2009) Patterns of persistent DNA damage associated with sun exposure and the glutathione S-transferase M1 genotype in melanoma patients. Photochem Photobiol 85:379-86
Su, Yuzhuo; Thakur, Sunitha B; Karimi, Sasan et al. (2008) Spectrum separation resolves partial-volume effect of MRSI as demonstrated on brain tumor scans. NMR Biomed 21:1030-42
Hubbard, Karen; Steinberg, Mark L; Hill, Helene et al. (2008) Mitochondrial DNA deletions in skin from melanoma patients. Ethn Dis 18:S2-38-43
Dudu, Veronica; Ramcharan, Melissa; Gilchrist, M Lane et al. (2008) Liposome delivery of quantum dots to the cytosol of live cells. J Nanosci Nanotechnol 8:2293-300

Showing the most recent 10 out of 14 publications