The University of California, Davis (UC Davis) is requesting continued support for the Clinical and Translational Science Center (CTSC). Since its initiation, the UC Davis CTSC has been firmly established as a major local, regional, and national leader in transforming the clinical and translational research enterprise and has received enthusiastic support from throughout UC Davis. The CTSC has created an extensive community of partners, ranging from the UC Davis Health System, colleges and schools to local community partners, regional partners including the University of Nevada and national partners, and other CTSA sites. The CTSC has fostered a cadre of successful trainees that are well prepared for a career trajectory in clinical and translational research, built an extensive infrastructure to support trainees, investigators, and community partners, and emerged as a major contributor to national CTSA goals. At the end of the initial funding period, the UC Davis CTSC is an organization that is: (1) responsive and familiar to investigators;(2) flexible;(3) versatile;(4) well-linked to university leadership, to participating academic units, and to the community;and (5) actively reducing barriers and facilitating translation of research gains into medical practice. The key features of our program are: education programs focused on """"""""team science"""""""";flexible Infrastructure;extensive collaborations across UC Davis;and engagement of local, regional, and national partners. The CTSC has played major leadership roles in establishing the national CTSA Consortium, and has been a leader or collaborator on 15 CTSA supplemental awards. In the next grant period, the CTSC will focus on 3 goals firmly anchored in our institutional fabric, the community, and the CTSA Consortium: (1) Completion of a comprehensive service and resource toolset for the research community;(2) Education and training of a well prepared workforce of trainees, staff, and investigators;and (3) Ensuring translational research is advanced to improve human health across the lifespan. To realize these goals, the CTSC will remain under the continued leadership of Lars Berglund, MD, PhD, supported by a cadre of directors and associate directors overseeing individual CTSC programs, and guided by a comprehensive committee structure designed to firmly anchor the CTSC with Institutional leadership, faculty, trainees, the community, and the national CTSA Consortium.

Public Health Relevance

The UC Davis CTSC has established a strong training and infrastructure resource to support and promote health research. Through the CTSC, research findings relevant to health and disease are made available to health professionals and community members. In addition, the UC Davis CTSC is part of a national network to ensure a broad-based information exchange between scientists, health professionals, and community members.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
8UL1TR000002-07
Application #
8278511
Study Section
Special Emphasis Panel (ZRR1-CR-1 (01))
Program Officer
Sufian, Meryl
Project Start
2006-09-30
Project End
2016-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
7
Fiscal Year
2012
Total Cost
$3,093,280
Indirect Cost
$1,084,656
Name
University of California Davis
Department
Type
Schools of Medicine
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
Goodman, Laura F; Chuluun, Erdenetsetseg; Sanjaa, Burmaa et al. (2018) A Nationwide Assessment of Pediatric Surgical Capacity in Mongolia. World J Surg 42:3432-3442
Shapiro, Brian P; Ambrosius, Walter T; Blackshear, Joseph L et al. (2018) Impact of Intensive Versus Standard Blood Pressure Management by Tertiles of Blood Pressure in SPRINT (Systolic Blood Pressure Intervention Trial). Hypertension 71:1064-1074
Rocco, Michael V; Sink, Kaycee M; Lovato, Laura C et al. (2018) Effects of Intensive Blood Pressure Treatment on Acute Kidney Injury Events in the Systolic Blood Pressure Intervention Trial (SPRINT). Am J Kidney Dis 71:352-361
Henderson, Timothy; Chen, Mingyi; Darrow, Morgan A et al. (2018) Alterations in cancer stem-cell marker CD44 expression predict oncologic outcome in soft-tissue sarcomas. J Surg Res 223:207-214
Holmes-Rovner, Margaret; Srikanth, Akshay; Henry, Stephen G et al. (2018) Decision aid use during post-biopsy consultations for localized prostate cancer. Health Expect 21:279-287
Mayadev, Jyoti; Lim, Jihoon; Durbin-Johnson, Blythe et al. (2018) Smoking Decreases Survival in Locally Advanced Cervical Cancer Treated With Radiation. Am J Clin Oncol 41:295-301
Norman, Jennifer E; Aung, Hnin H; Wilson, Dennis W et al. (2018) Inhibition of perilipin 2 expression reduces pro-inflammatory gene expression and increases lipid droplet size. Food Funct 9:6245-6256
Hagemann, L Tamina; McCartney, Mitchell M; Fung, Alexander G et al. (2018) Portable combination of Fourier transform infrared spectroscopy and differential mobility spectrometry for advanced vapor phase analysis. Analyst 143:5683-5691
Beddhu, Srinivasan; Greene, Tom; Boucher, Robert et al. (2018) Intensive systolic blood pressure control and incident chronic kidney disease in people with and without diabetes mellitus: secondary analyses of two randomised controlled trials. Lancet Diabetes Endocrinol 6:555-563
Meyer, Oanh L; Liu, Xiaoyan Lucia; Tancredi, Daniel et al. (2018) Acculturation level and caregiver outcomes from a randomized intervention trial to enhance caregivers' health: evidence from REACH II. Aging Ment Health 22:730-737

Showing the most recent 10 out of 476 publications