The Overarching Goal of the Indiana Clinical and Translational Science Institute (CTSI) is to transformthe Darticipating institutions to create an environment that facilitates the conduct of biomedical research. Mission Statement: """"""""To increase translational biomedical research and improve the health of the people of Indiana and beyond."""""""" To this end, we have developed new mechanisms to acceleratetranslational research, including enhanced educational programs to train translational researchers,a newly designed community engagement activity to produce effective and bidirectional community partnerships, streamlining of all available research infra- structure to acceleratetranslational projects,and partnering with commercial and philanthropic organizations in Indiana. Throughout all of these efforts runs the critical link of our medical informatics program, enabling all parties to interact in a facile and responsive and prompt manner. Thus, the Indiana CTSI brings together the resourcesof an entire state. In short, it will provide to the national network of CTSAs: A true statewide laboratory to experiment with innovative methods aimed at transforming researchin biomedical sciences, health economy, health care delivery, and health policy. The 5 Specific goals of the Indiana CTSI: I. Create Translational Research Acceleration Programsand Support Pilot Projects by providing investigators and consumers with strategic leadership and mentorship to identify, evaluate, and support innovative and important pilot researchat each step of the translational cycle. . Train a new cadre of Translational Researchersby strengthening existing programs and creating new ones to educate trainees and engage faculty in the translational sciences. HI. Foster Robust Community Engagement by creating novel programs with bidirectional participation (i.e., from academia to the community and back again), such as the Indiana Community Health Enhancement Program (CHEP) and pilot programs in Health Econmics, and Rural and Global Health. IV. Build Facile and Comprehensive Research Resourcesand Technologies by transforming the existing and new research infrastructure into innovative programssuch as the Participant and Clinical Interaction Resources (PCIR), Translational Technology Resources(TTR). Research Ethics, Biostatistics and Design Program (BDP), and uniquely, biomedical engineering and bio-nanotechnology to facilitate health research. V. Leverage the Resources of the Greater Indiana Community by connecting to a broad array of resources from multiple partner institutions throughout the state to realize the full potential of the Indiana CTSI.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
8UL1TR000006-05
Application #
8299033
Study Section
Special Emphasis Panel (ZRR1-SRC (99))
Program Officer
Wilson, Todd
Project Start
2008-05-19
Project End
2013-10-31
Budget Start
2012-05-01
Budget End
2013-10-31
Support Year
5
Fiscal Year
2012
Total Cost
$4,363,395
Indirect Cost
$1,102,122
Name
Indiana University-Purdue University at Indianapolis
Department
Psychiatry
Type
Schools of Medicine
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Macy, Jonathan T; Moser, Elizabeth A S; Hirsh, Adam T et al. (2018) Factors associated with seeking preventive dental care: an integrative model exploration of behaviors in Mexican immigrants in Midwest America. BMC Oral Health 18:37
Brunt, Elizabeth M; Kleiner, David E; Wilson, Laura A et al. (2018) Improvements in Histologic Features and Diagnosis associated with Improvement in Fibrosis in NASH: Results from the NASH Clinical Research Network Treatment Trials. Hepatology :
Mather, Kieren J; Considine, Robert V; Hamilton, LaTonya et al. (2018) Combination GLP-1 and Insulin Treatment Fails to Alter Myocardial Fuel Selection vs. Insulin Alone in Type 2 Diabetes. J Clin Endocrinol Metab 103:3456-3465
Harlow, Kathryn E; Africa, Jonathan A; Wells, Alan et al. (2018) Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease. J Pediatr 198:76-83.e2
Chumin, Evgeny J; Goñi, Joaquín; Halcomb, Meredith E et al. (2018) Differences in White Matter Microstructure and Connectivity in Nontreatment-Seeking Individuals with Alcohol Use Disorder. Alcohol Clin Exp Res 42:889-896
Middleton, Michael S; Van Natta, Mark L; Heba, Elhamy R et al. (2018) Diagnostic accuracy of magnetic resonance imaging hepatic proton density fat fraction in pediatric nonalcoholic fatty liver disease. Hepatology 67:858-872
Africa, Jonathan A; Behling, Cynthia A; Brunt, Elizabeth M et al. (2018) In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis. Clin Gastroenterol Hepatol 16:438-446.e1
Ajmera, Veeral; Belt, Patricia; Wilson, Laura A et al. (2018) Among Patients With Nonalcoholic Fatty Liver Disease, Modest Alcohol Use Is Associated With Less Improvement in Histologic Steatosis and Steatohepatitis. Clin Gastroenterol Hepatol 16:1511-1520.e5
Fontana, M; Eckert, G J; Keels, M A et al. (2018) Fluoride Use in Health Care Settings: Association with Children's Caries Risk. Adv Dent Res 29:24-34
Plawecki, Martin H; Windisch, Kyle A; Wetherill, Leah et al. (2018) Alcohol affects the P3 component of an adaptive stop signal task ERP. Alcohol 70:1-10

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