Florida is a demographically and geographically diverse state. The University of Florida (UF) and Florida State University (FSU) CTSA hub will work within this environment to further the mission to improve human health by accelerating the translation of scientific discoveries and the implementation of evidence-based best practices for the diagnosis, treatment, prevention and cure of human diseases across the lifespan. The UF-FSU hub vision is ?think globally, act locally?, offering research opportunities to underserved participants in North and North Central Florida, creating innovative career development and training opportunities, as well as collaborating across the country with the Accelerated Clinical Trials Network and PCORnet. Research strengths include precision medicine, team science, community engagement, implementation science and informatics which are conducted in diverse settings through the OneFlorida Clinical Research Consortium. The 2019-2024 period represents the next phase of evolution from creating a clinical and translational science infrastructure to enhancing the local, state and national impact of CTSI-led science. During this period, FSU will be integrated across all components and will engage six additional colleges. Hub activities will be centered around four strategic goals: (1) chart new pathways for developing the translational workforce by taking UF?s success in career development and translating this success to the FSU and historically black colleges and universities; (2) strengthen the capacity of the learning health system environment and develop transferable models for embedding translational science into the clinical enterprise by further integrating data and software, developing multi-site pilots in healthcare institutions serving unique patient populations and building on the success of the personalized medicine program to use genomics data to improve patient outcomes; (3) expand statewide collaborations and opportunities to advance a participant-centered research agenda that reflects the health priorities and diversity of the catchment area by continuing to strengthen stakeholder engagement and trust in research through the HealthStreet Program and enhance collaboration with policy stakeholders from Florida Medicaid, Florida surgeon general and others; and (4) strengthen regional and national collaborations to accelerate the collective impact of the CTSA network through continued work with ACT, PCORnet, genomic medicine, aging and metabolomics. Throughout this important work, the UF-FSU hub will remain dedicated to supporting the recruitment, retention and career development of underrepresented minority and disabled trainees and faculty. Integral to the success of the proposed work, the UF-FSU hub will further integrate health care and research in Florida guided by four keys to success: (1) organizational alignment, (2) clinical informatics, (3) clinician and stakeholder engagement, and (4) strong support from implementation and improvement science expertise.

Public Health Relevance

The University of Florida (UF) and Florida State University (FSU) CTSA hub will work within the demographically and geographically diverse state of Florida to improve human health by accelerating the translation of scientific discoveries and the implementation of evidence-based best practices for the diagnosis, treatment, prevention and cure of human diseases across the lifespan. The 2019-2024 period represents the next phase of evolution from creating a clinical and translational science infrastructure to enhancing the local, state and national impact of CTSI-led science with a special emphasis on underserved and unique patient populations.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
2UL1TR001427-05
Application #
9902684
Study Section
Special Emphasis Panel (ZTR1)
Program Officer
Brazhnik, Olga
Project Start
2015-08-15
Project End
2024-06-30
Budget Start
2019-07-02
Budget End
2020-06-30
Support Year
5
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Florida
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Park, Haesuk; Wang, Wei; Henry, Linda et al. (2018) Impact of all-oral direct-acting antivirals on clinical and economic outcomes in chronic hepatitis C patients in the U.S. Hepatology :
Boissoneault, Jeff; Letzen, Janelle; Lai, Song et al. (2018) Static and dynamic functional connectivity in patients with chronic fatigue syndrome: use of arterial spin labelling fMRI. Clin Physiol Funct Imaging 38:128-137
Nickerson, Paul; Baharloo, Raheleh; Davoudi, Anis et al. (2018) Comparison of Gaussian Processes Methods to Linear methods for Imputation of Sparse Physiological Time Series. Conf Proc IEEE Eng Med Biol Soc 2018:4106-4109
Pertzborn, Matthew C; Prabhakaran, Sreekala; Hardy, Alicia et al. (2018) Direct Observed Therapy of Inhaled Corticosteroids for Asthma at School or Daycare. Pediatr Allergy Immunol Pulmonol 31:226-229
Cardel, Michelle I; Min, Yuan-I; Sims, Mario et al. (2018) Association of psychosocial stressors with metabolic syndrome severity among African Americans in the Jackson Heart Study. Psychoneuroendocrinology 90:141-147
Loftus, Tyler J; Morrow, Megan L; Lottenberg, Lawrence et al. (2018) Occult bowel injury after blunt abdominal trauma. Am J Surg :
Loftus, Tyler J; Brakenridge, Scott C; Murphy, Travis W et al. (2018) Anemia and blood transfusion in elderly trauma patients. J Surg Res 229:288-293
Filipp, S L; Cardel, M; Hall, J et al. (2018) Characterization of adult obesity in Florida using the OneFlorida clinical research consortium. Obes Sci Pract 4:308-317
Wenger, Nanette K; Arnold, Anita; Bairey Merz, C Noel et al. (2018) Hypertension Across a Woman's Life Cycle. J Am Coll Cardiol 71:1797-1813
Fedele, David A; Janicke, David M; McQuaid, Elizabeth L et al. (2018) A Behavioral Family Intervention for Children with Overweight and Asthma. Clin Pract Pediatr Psychol 6:259-269

Showing the most recent 10 out of 602 publications