Cyclodextrins are conversion products of starch and when suitable chemically modified represent potent solubilizers of lipophiles. In the chemical part of the project the rules for chemical modification of cyclodextrins were established. In the biomedical part of the project (a) hydroxypropylcyclotrins were used to study the effects of supplementation of adrenal and sex hormones in rats and .(b) cyclodextrin sulfates were found to inhibit replication of HIV1.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Intramural Research (Z01)
Project #
1Z01AG000046-20
Application #
3808845
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
20
Fiscal Year
1990
Total Cost
Indirect Cost
Name
National Institute on Aging
Department
Type
DUNS #
City
State
Country
United States
Zip Code