Between-group analysis using magnetic resonance imaging (MRI) showed that subjects with mild Alzheimer's disease (AD), compared with sex- and age-matched controls, had significantly smaller mean medial temporal lobe volume, except for the right anterior parahippocampal gyrus, and lower scores on most neuropsychological measures. Discriminant analysis using demographic variables and the medial temporal lobe volumes produced 97% correct group classification. Using volumes only, correct classification wa 91%. Equivalent classification was obtained using only left hemispheric volumes.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Intramural Research (Z01)
Project #
1Z01AG000411-07
Application #
2565696
Study Section
Special Emphasis Panel (LN)
Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
National Institute on Aging
Department
Type
DUNS #
City
State
Country
United States
Zip Code