It is the purpose of this study to adapt the methodology used to measure the levels of specific mRNAs in biopsies of human skin, particularly from chronic wounds. Specifically the polymerase chain reaction is being utilized to measure mRNA levels for collagenase and for collagen. Also the levels of these mRNAs are being assayed in fibroblasts cultured from skin biopsies of individuals of varying age to identify possible alterations in gene regulation.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Intramural Research (Z01)
Project #
1Z01AG000720-01
Application #
3808953
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1990
Total Cost
Indirect Cost
Name
National Institute on Aging
Department
Type
DUNS #
City
State
Country
United States
Zip Code