In this year, we have published several minor studies. The bulk of our effors has been devoted to collecting and carrying out whole genome analyses of PArkinson's disease. This project is now complete and the description of our data on this topic will be published in Lancet Neurology in October .

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Intramural Research (Z01)
Project #
1Z01AG000952-05
Application #
7326496
Study Section
(LNG)
Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
2006
Total Cost
Indirect Cost
Name
Aging
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Hardy, John (2006) No definitive evidence for a role for the environment in the etiology of Parkinson's disease. Mov Disord 21:1790-1
Fidani, Liana; Kalinderi, Kallirhoe; Bostantjopoulou, Sevasti et al. (2006) Association of the Tau haplotype with Parkinson's disease in the Greek population. Mov Disord 21:1036-9
Fung, Hon-Chung; Chen, Chiung-Mei; Hardy, John et al. (2006) Lack of G2019S LRRK2 mutation in a cohort of Taiwanese with sporadic Parkinson's disease. Mov Disord 21:880-1
Clarimon, Jordi; Scholz, Sonja; Fung, Hon-Chung et al. (2006) Conflicting results regarding the semaphorin gene (SEMA5A) and the risk for Parkinson disease. Am J Hum Genet 78:1082-4; author reply 1092-4
McInerney-Leo, Aideen; Hadley, Donald W; Gwinn-Hardy, Katrina et al. (2005) Genetic testing in Parkinson's disease. Mov Disord 20:1-10
Clarimon, Jordi; Johnson, Janel; Dogu, Okan et al. (2005) Defining the ends of Parkin exon 4 deletions in two different families with Parkinson's disease. Am J Med Genet B Neuropsychiatr Genet 133:120-3
Hernandez, Dena; Paisan Ruiz, Coro; Crawley, Anthony et al. (2005) The dardarin G 2019 S mutation is a common cause of Parkinson's disease but not other neurodegenerative diseases. Neurosci Lett 389:137-9
Hardy, John; Lees, Andrew J (2005) Parkinson's disease: a broken nosology. Mov Disord 20 Suppl 12:S2-4
Miller, David W; Crawley, Anthony; Gwinn-Hardy, Katrina et al. (2005) Unaltered alpha-synuclein blood levels in juvenile Parkinsonism with a parkin exon 4 deletion. Neurosci Lett 374:189-91
Martinez, Maria; Brice, Alexis; Vaughan, Jenny R et al. (2005) Apolipoprotein E4 is probably responsible for the chromosome 19 linkage peak for Parkinson's disease. Am J Med Genet B Neuropsychiatr Genet 136:72-4

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