A series of monoclonal antibodies directed against RNA polymerase II have been prepared. Three of these lines are able to inhibit transcription using an in vitro assay. The monoclonal, all of which are IgM, have not yet been characterized regarding which subunit they recognize.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Intramural Research (Z01)
Project #
1Z01AI000446-02
Application #
3960620
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Niaid Extramural Activities
Department
Type
DUNS #
City
State
Country
United States
Zip Code