A full size cDNA copy of gene 9 (the gene that codes for the outer capsid glycoprotein VP7) from porcine rotavirus strain OSU has been cloned and its restriction pattern analyzed. We are in the process of sequencing this gene and transferring it to expression vectors. We are employing the expression vector system developed by Dr. Inouye at Stoneybrook University. Currently, different clones of the vectors containing copies of gene 9 have been constructed and are being analyzed for expression.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Intramural Research (Z01)
Project #
1Z01AI000450-01
Application #
4688559
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Niaid Extramural Activities
Department
Type
DUNS #
City
State
Country
United States
Zip Code