Classical class I molecules present endogenous peptide antigens for recognition by cytotoxic T lymphocytes. Nonclassical class I (class Ib) molecules, although similar in structure to classical class I molecules, have an unknown function. In this project we are studying the cell biology biochemistry, and function of two representative mouse class Ib molecules, Q7b and mCD1.1, with the ultimate goal of determining the role of these molecules in anti-viral immune responses.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Intramural Research (Z01)
Project #
1Z01AI000731-04
Application #
6099054
Study Section
Special Emphasis Panel (LVD)
Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
1998
Total Cost
Indirect Cost
City
State
Country
United States
Zip Code