This project is designed to prepare a GMP quality investigational HIV vaccine and cytokine adjuvant and complete the preclinical and laboratory studies needed to begin a clinical trial. Healthy, HIV-uninfected volunteers will be enrolled in a double-blind, placebo-controlled Phase I study which will evaluate the safety and immunogenicity of a DNA plasmid HIV vaccine administered either concomitantly with the plasmid cytokine adjuvant or sequentially with adjuvant given two days after the vaccine.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Intramural Research (Z01)
Project #
1Z01AI005043-01
Application #
6696474
Study Section
(VPP)
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
2002
Total Cost
Indirect Cost
Name
Niaid Extramural Activities
Department
Type
DUNS #
City
State
Country
United States
Zip Code