A vaccine against West Nile Virus would provide a public health benefit by preventing infection and disease by this virus. Genetic vaccines (DNA) expressing different proteins associated with the virus, including core (C), pre membrane (PrM) and envelope (E) have been investigated for their protective effects. Mechanisms of infection and immune correlates of protection were also studied.
| Collins, Christopher M; Speck, Samuel H (2012) Tracking murine gammaherpesvirus 68 infection of germinal center B cells in vivo. PLoS One 7:e33230 |
| Sheets, Rebecca L; Stein, Judith; Manetz, T Scott et al. (2006) Biodistribution of DNA plasmid vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile virus is similar, without integration, despite differing plasmid backbones or gene inserts. Toxicol Sci 91:610-9 |
