Patients with systemic lupus were found to have an increase in mutations in their T cells as defined by their ability to grow in the presence of 6-thioguanine. The extent to which this results from a primary abnormality and the extent to which drugs contribute remains to be determined.

Project Start
Project End
Budget Start
Budget End
Support Year
17
Fiscal Year
1991
Total Cost
Indirect Cost
Name
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Department
Type
DUNS #
City
State
Country
United States
Zip Code