The feasibility of associating small polypeptides with micelles has been demonstrated. A 9-mer including part of a neutralizing site of hemaglutin in was synthesized and 2 isoleucines were attached to each end. The resultant peptide associated to greater than 99% with non-ionic surfactants in the L1 phase (micelles). This system will now be used to study the structure and dynamics of the peptide/micelle complex.

Agency
National Institute of Health (NIH)
Institute
Food and Drug Administration (FDA)
Type
Intramural Research (Z01)
Project #
1Z01BI004010-01
Application #
6161180
Study Section
Special Emphasis Panel (LP)
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1997
Total Cost
Indirect Cost